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Tocris/Sphingosine-1-phosphate/1370/1/1 mg

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Tocris/Sphingosine-1-phosphate/1370/1/1 mg

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Tocris Bioscience

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1370/1

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4000-520-616

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Description:EndogenousagoNISTatS1P_1-5

ChemicalName:(E)-D-erythro-2-amino-1-(dihydrogenphosphate)-4-octadecene-1,3-diol

Purity:≥98%(HPLC)

BIOLOGicalActivityTechnicalDataDatasheetsReferences

BiologicalActivity

Endogenoussecondmessengerinvolvedinthecontrolofcellproliferationandmotility,andCa²⁺mobilization.Actsasanagonistatsphingosine-1-phosphatereceptors(S1P_1-5)andasanactivatorofGPR3,GPR6andGPR12.Effectorsregulatedincludep38MAPkinase,PLC,adenylylcyclase,myosinlightchainphosphataseandfocaladhesionkinase.

TechnicalData

M.Wt	379.48
Formula	C₁₈H₃₈NO₅P
Storage	Desiccateat+4°C
Purity	≥98%(HPLC)
CASNumber	26993-30-6
PubChemID	5283560
InChIKey	DUYSYHSSBDVJSM-KRWOKUGFSA-N
Smiles	O[C@H](/C=C/CCCCCCCCCCCCC)[C@@H](N)COP(O)(O)=O

Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.

AllTocrisproductsareintendedforlaboratoryresearchuseonly.

PreparingStockSolutions

Thefollowingdataisbasedontheproductmolecularweight379.48.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.

Concentration/SolventVolume/Mass	1mg	5mg	10mg
1mM	2.64mL	13.18mL	26.35mL
5mM	0.53mL	2.64mL	5.27mL
10mM	0.26mL	1.32mL	2.64mL
50mM	0.05mL	0.26mL	0.53mL

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