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Tocris/TUG 891/4601/10/10 mg
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4000-520-616
Description:PotentandselectiveFFA4(GPR120)agoNIST
ChemicalName:4-[(4-Fluoro-4'-methyl[1,1'-biphenyl]-2-yl)methoxy]-benzenepropanoicacid
Purity:≥99%(HPLC)
BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences
BiologicalActivity
PotentFFA4(GPR120)agonist(pEC50valuesare7.36and7.77forhumanandmouseGPR120respectively).SelectiveforGPR120overfreefattyacidreceptors(pEC50=4.19forFFA1;displaysnoactivityatFFA2orFFA3).Cellpermeable.
LicensingInformation
SoldunderlicensefromtheUniversityofSouthernDenmark.
CompoundLibraries
TUG891isalsoofferedaspartoftheTocriscreenPlus.FindoutmoreaboutcompoundlibrariesavailablefromTocris.
TechnicalData
M.Wt | 364.41 |
Formula | C23H21FO3 |
Storage | StoreatRT |
Purity | ≥99%(HPLC) |
CASNumber | 1374516-07-0 |
PubChemID | 57522038 |
InChIKey | LPGBXHWIQNZEJB-UHFFFAOYSA-N |
Smiles | FC1=CC(COC2=CC=C(CCC(O)=O)C=C2)=C(C3=CC=C(C)C=C3)C=C1 |
Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.
AllTocrisproductsareintendedforlaboratoryresearchuseonly.
SolubilityData
Solvent | MaxConc.mg/mL | MaxConc.mM | |
---|---|---|---|
Solubility | |||
DMSO | 36.44 | 100 |
PreparingStockSolutions
Thefollowingdataisbasedontheproductmolecularweight364.41.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.
Concentration/SolventVolume/Mass | 1mg | 5mg | 10mg |
---|---|---|---|
1mM | 2.74mL | 13.72mL | 27.44mL |
5mM | 0.55mL | 2.74mL | 5.49mL |
10mM | 0.27mL | 1.37mL | 2.74mL |
50mM | 0.05mL | 0.27mL | 0.55mL |
MolarityCalculator
MolarityCalculator
Calculatethemass,volume,orconcentrationrequiredforasolution.
ReconstitutionCalculator
ReconstitutionCalculator
DilutionCalculator
DilutionCalculator
Calculatethedilutionrequiredtoprepareastocksolution.
ProductDatasheets
CertificateofAnalysis/ProductDatasheet
SafetyDatasheet
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