Tocris厂家直采，平行进口 Tocris Bioscience产品促销,Tocris/Fasentin/6100/50/50 mg,受体,生物分子,生化试剂,,Tocris Bioscience蚂蚁淘商城

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Tocris/Fasentin/6100/50/50 mg

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Tocris Bioscience

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6100/50

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4000-520-616

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Description:GLUT1/GLUT4inhibitor;alsoFas-sensitizer

ChemicalName:N-(4-Chloro-3-(trifluoromethyl)phenyl)-3-oxobutanamide

Purity:≥98%(HPLC)

BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences

BiologicalActivity

GLUT1andGLUT4inhibitor(IC₅₀=68μM).PreferentiallyinhibitsGLUT4overGLUT1.SensitizesFasreceptorinarangeoftumorcelllines(IC₅₀=20μM)bymodulatingtheextrinsicapoptoticpathwaydownstreamofTNFreceptorsbutupstreamofeffectorcaspases.

TechnicalData

M.Wt	279.64
Formula	C₁₁H₉ClF₃NO₂
Storage	Storeat-20°C
Purity	≥98%(HPLC)
CASNumber	392721-37-8
PubChemID	879520
InChIKey	GNYIJZMBLZXJEJ-UHFFFAOYSA-N
Smiles	CC(CC(NC1=CC(C(F)(F)F)=C(C=C1)Cl)=O)=O

Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.

AllTocrisproductsareintendedforlaboratoryresearchuseonly.

SolubilityData

	Solvent	MaxConc.mg/mL	MaxConc.mM
Solubility
	DMSO	27.96	100
	ethanol	27.96	100

PreparingStockSolutions

Thefollowingdataisbasedontheproductmolecularweight279.64.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.

Concentration/SolventVolume/Mass	1mg	5mg	10mg
1mM	3.58mL	17.88mL	35.76mL
5mM	0.72mL	3.58mL	7.15mL
10mM	0.36mL	1.79mL	3.58mL
50mM	0.07mL	0.36mL	0.72mL

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BiologicalActivity

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