Tocris中国采购 Tocris小分子,Tocris/AF-DX 116/1105/50/50 mg,受体,生物分子,生化试剂,,Tocris Bioscience蚂蚁淘商城

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Tocris/AF-DX 116/1105/50/50 mg

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Tocris Bioscience

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1105/50

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4000-520-616

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Description:SelectiveM₂antagoNIST

AlternativeNames:Otenzepad

ChemicalName:11-[[2-[(Diethylamino)methyl]-1-piperidinyl]acetyl]-5,11-dihydro-6H-pyrido[2,3-b][1,4]benzodiazepin-6-one

Purity:≥98%(HPLC)

BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences

BiologicalActivity

SelectiveM₂muscarinicreceptorantagonist.K_ivaluesare64,417,786,211and5130nMforhumanrecombinantM₂,M₁,M₃,M₄andM₅muscarinicreceptors,respectively.

LicensingInformation

SoldwiththepermissionofBoehringerIngelheimGmbH

CompoundLibraries

AF-DX116isalsoofferedaspartoftheTocriscreenPlus.FindoutmoreaboutcompoundlibrariesavailablefromTocris.

TechnicalData

M.Wt	421.54
Formula	C₂₄H₃₁N₅O₂
Storage	StoreatRT
Purity	≥98%(HPLC)
CASNumber	102394-31-0
PubChemID	107867
InChIKey	UBRKDAVQCKZSPO-UHFFFAOYSA-N
Smiles	CCN(CC)CC1CCCCN1CC(=O)N1C2=C(C=CC=C2)C(=O)NC2=CC=CN=C12

Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.

AllTocrisproductsareintendedforlaboratoryresearchuseonly.

SolubilityData

	Solvent	MaxConc.mg/mL	MaxConc.mM
Solubility
Solubility	DMSO	10.54	25mMwithgentlewarming

PreparingStockSolutions

Thefollowingdataisbasedontheproductmolecularweight421.54.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.

Concentration/SolventVolume/Mass	1mg	5mg	10mg
1mM	2.37mL	11.86mL	23.72mL
5mM	0.47mL	2.37mL	4.74mL
10mM	0.24mL	1.19mL	2.37mL
50mM	0.05mL	0.24mL	0.47mL

ProductDatasheets

CertificateofAnalysis/ProductDatasheet

SafetyDatasheet

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