美国Tocris公司 Tocris配体,Tocris/AF-DX 384/1345/50/50 mg,受体,生物分子,生化试剂,,Tocris Bioscience蚂蚁淘商城

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Tocris/AF-DX 384/1345/50/50 mg

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Tocris Bioscience

货号 /

1345/50

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4000-520-616

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Description:PotentM₂/M₄antagoNIST

ChemicalName:N-[2-[2-[(Dipropylamino)methyl]-1-piperidinyl]ethyl]-5,6-dihydro-6-oxo-11H-pyrido[2,3-b][1,4]benzodiazepine-11-carboxamide

Purity:≥98%(HPLC)

BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences

BiologicalActivity

PotentM₂/M₄selectiveantagonist(pK_ivaluesare8.22,8.00,7.51,7.18and6.27athumanM₂,M₄,M₁,M₃andM₅receptorsrespectively).

TechnicalData

M.Wt	478.64
Formula	C₂₇H₃₈N₆O₂
Storage	StoreatRT
Purity	≥98%(HPLC)
CASNumber	118290-26-9
PubChemID	119357
InChIKey	MZDYABXXPZNUCT-UHFFFAOYSA-N
Smiles	CCCN(CCC)CC1CCCCN1CCNC(=O)N1C2=C(C=CC=C2)C(=O)NC2=C1N=CC=C2

Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.

AllTocrisproductsareintendedforlaboratoryresearchuseonly.

SolubilityData

	Solvent	MaxConc.mg/mL	MaxConc.mM
Solubility
	DMSO	23.93	50
	ethanol	4.79	10

PreparingStockSolutions

Thefollowingdataisbasedontheproductmolecularweight478.64.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.

Concentration/SolventVolume/Mass	1mg	5mg	10mg
1mM	2.09mL	10.45mL	20.89mL
5mM	0.42mL	2.09mL	4.18mL
10mM	0.21mL	1.04mL	2.09mL
50mM	0.04mL	0.21mL	0.42mL

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BiologicalActivity

TechnicalData

SolubilityData

PreparingStockSolutions

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