Tocris抗体 Tocris化合物筛选文库,Tocris/AM 4668/5789/50/50 mg,受体,生物分子,生化试剂,,Tocris Bioscience蚂蚁淘商城

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Tocris/AM 4668/5789/50/50 mg

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Tocris Bioscience

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5789/50

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4000-520-616

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Description:PotentFFA1(GPR40)agoNIST

ChemicalName:(βS)-β-[4-[[4-Methyl-2-[4-(trifluoromethyl)phenyl]-5-thiazolyl]methoxy]phenyl)-3-isoxazolepropanoicacid

Purity:≥98%(HPLC)

BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences

BiologicalActivity

PotentFFA1(GPR40)agonist(EC₅₀=3.6nMinanIP₃assayinGPR40transfectedA9cells).Inhibitsinsulinsecretionfromisolatedpancreaticislets.Reducesbloodglucoselevelsfollowingoralglucosechallengeinmice.Orallybioavailable.

TechnicalData

M.Wt	488.48
Formula	C₂₄H₁₉F₃O₄S
Storage	Storeat-20°C
Purity	≥98%(HPLC)
CASNumber	1011531-27-3
PubChemID	24897670
InChIKey	BMLGZNVPWRUVNM-IBGZPJMESA-N
Smiles	CC1=C(COC2=CC=C(C=C2)[C@H](CC(O)=O)C2=NOC=C2)SC(=N1)C1=CC=C(C=C1)C(F)(F)F

Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.

AllTocrisproductsareintendedforlaboratoryresearchuseonly.

SolubilityData

	Solvent	MaxConc.mg/mL	MaxConc.mM
Solubility
	DMSO	48.85	100
	ethanol	48.85	100

PreparingStockSolutions

Thefollowingdataisbasedontheproductmolecularweight488.48.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.

Concentration/SolventVolume/Mass	1mg	5mg	10mg
1mM	2.05mL	10.24mL	20.47mL
5mM	0.41mL	2.05mL	4.09mL
10mM	0.2mL	1.02mL	2.05mL
50mM	0.04mL	0.2mL	0.41mL

ProductDatasheets

CertificateofAnalysis/ProductDatasheet

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BiologicalActivity

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PreparingStockSolutions

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