商品信息
联系客服
郑重提醒:
无质量问题不接受退换货,下单前请仔细核对信息。
下单后请及时联系客服核对商品价格,订单生效后再付款。
Tocris/AM 580/0760/10/10 mg
免费咨询热线
4000-520-616
Description:Retinoicacidanalog;RARαagoNIST
ChemicalName:4-[(5,6,7,8-Tetrahydro-5,5,8,8-tetramethyl-2-naphthalenyl)carboxamido]benzoicacid
Purity:≥98%(HPLC)
BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences
BiologicalActivity
AnanalogofretinoicacidthatactsasaselectiveRARαagonist(EC50valuesare0.3,8.6and13nMforRARα,RARβandRARγrespectively).SignificantlyinducesIL-4,IL-5andIL-13andinhibitsIL-12andIFNγsynthesis,andinducescelldifferentiationwithover7timestheactivityofretinoicacidinvitro.
CompoundLibraries
AM580isalsoofferedaspartoftheTocriscreenPlusandTocriscreenStemCellToolbox.FindoutmoreaboutcompoundlibrariesavailablefromTocris.
TechnicalData
M.Wt | 351.44 |
Formula | C22H25NO3 |
Storage | StoreatRT |
Purity | ≥98%(HPLC) |
CASNumber | 102121-60-8 |
PubChemID | 2126 |
InChIKey | SZWKGOZKRMMLAJ-UHFFFAOYSA-N |
Smiles | CC1(C)CCC(C)(C)C2=CC(=CC=C12)C(=O)NC1=CC=C(C=C1)C(O)=O |
Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.
AllTocrisproductsareintendedforlaboratoryresearchuseonly.
SolubilityData
Solvent | MaxConc.mg/mL | MaxConc.mM | |
---|---|---|---|
Solubility | |||
DMSO | 17.57 | 50 | |
ethanol | 35.14 | 100 |
PreparingStockSolutions
Thefollowingdataisbasedontheproductmolecularweight351.44.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.
Concentration/SolventVolume/Mass | 1mg | 5mg | 10mg |
---|---|---|---|
1mM | 2.85mL | 14.23mL | 28.45mL |
5mM | 0.57mL | 2.85mL | 5.69mL |
10mM | 0.28mL | 1.42mL | 2.85mL |
50mM | 0.06mL | 0.28mL | 0.57mL |
MolarityCalculator
MolarityCalculator
Calculatethemass,volume,orconcentrationrequiredforasolution.
ReconstitutionCalculator
ReconstitutionCalculator
DilutionCalculator
DilutionCalculator
Calculatethedilutionrequiredtoprepareastocksolution.
ProductDatasheets
CertificateofAnalysis/ProductDatasheet
SafetyDatasheet
▍
品牌分类
▍
官网分类
▍
品牌问答
暂无品牌问答