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Tocris/GBR 12783 dihydrochloride/0513/50/50 mg
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4000-520-616
Description:Potent,selectivedopamineuptakeinhibitor
ChemicalName:1-(2-Diphenylmethoxyethyl)-4-(3-phenyl-2-propenyl)-piperazinedihydrochloride
Purity:≥99%(HPLC)
BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences
BiologicalActivity
Averypotentandselectiveinhibitorofdopamineuptake(IC50forinhibitionof[3H]-dopamineuptakeinratstriatalsynaptosomesis1.8nM).
TechnicalData
M.Wt | 485.5 |
Formula | C28H32N2O.2HCl |
Storage | Desiccateat-20°C |
Purity | ≥99%(HPLC) |
CASNumber | 67469-75-4 |
PubChemID | 24744862 |
InChIKey | HJDXBLLTRMCYNC-JFXLULTRSA-N |
Smiles | Cl[H].Cl[H].C(CN1CCN(CC=CC2=CC=CC=C2)CC1)OC(C1=CC=CC=C1)C1=CC=CC=C1 |
Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.
AllTocrisproductsareintendedforlaboratoryresearchuseonly.
SolubilityData
Solvent | MaxConc.mg/mL | MaxConc.mM | |
---|---|---|---|
Solubility | |||
DMSO | 24.27 | 50mMwithgentlewarming | |
ethanol | 2.43 | 5mMwithgentlewarming | |
water | 4.86 | 10mMwithgentlewarming |
PreparingStockSolutions
Thefollowingdataisbasedontheproductmolecularweight485.5.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.
Concentration/SolventVolume/Mass | 1mg | 5mg | 10mg |
---|---|---|---|
1mM | 2.06mL | 10.3mL | 20.6mL |
5mM | 0.41mL | 2.06mL | 4.12mL |
10mM | 0.21mL | 1.03mL | 2.06mL |
50mM | 0.04mL | 0.21mL | 0.41mL |
MolarityCalculator
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ReconstitutionCalculator
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DilutionCalculator
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ProductDatasheets
CertificateofAnalysis/ProductDatasheet
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