Tocris试剂采购中国Tocris Bioscience官网，价格更新,Tocris/KS 176/4169/50/50 mg,转运体,生物分子,生化试剂,,Tocris Bioscience蚂蚁淘商城

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Tocris/KS 176/4169/50/50 mg

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Tocris Bioscience

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4169/50

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4000-520-616

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Description:SelectiveBCRPinhibitor

ChemicalName:N-[4-(2-Hydroxyethyl)phenyl]-2-[(4-nitrobenzoyl)amino]benzamide

Purity:≥98%(HPLC)

BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences

BiologicalActivity

Selectiveinhibitorofthebreastcancerresistanceprotein(BCRP)multidrugtransporter(IC₅₀valuesare0.59and1.39μMinPheoAandHoechst33342assaysrespectively).DisplaysnoinhibitoryactivityagainstP-gporMRP1.

CompoundLibraries

KS176isalsoofferedaspartoftheTocriscreenPlus.FindoutmoreaboutcompoundlibrariesavailablefromTocris.

TechnicalData

M.Wt	405.4
Formula	C₂₂H₁₉N₃O₅
Storage	Storeat+4°C
Purity	≥98%(HPLC)
CASNumber	1253452-78-6
PubChemID	49779726
InChIKey	LTWQQWSXYYXVGA-UHFFFAOYSA-N
Smiles	OCCC1=CC=C(NC(C2=C(NC(C3=CC=C([N+]([O-])=O)C=C3)=O)C=CC=C2)=O)C=C1

Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.

AllTocrisproductsareintendedforlaboratoryresearchuseonly.

SolubilityData

	Solvent	MaxConc.mg/mL	MaxConc.mM
Solubility
Solubility	DMSO	40.54	100

PreparingStockSolutions

Thefollowingdataisbasedontheproductmolecularweight405.4.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.

Concentration/SolventVolume/Mass	1mg	5mg	10mg
1mM	2.47mL	12.33mL	24.67mL
5mM	0.49mL	2.47mL	4.93mL
10mM	0.25mL	1.23mL	2.47mL
50mM	0.05mL	0.25mL	0.49mL

ProductDatasheets

CertificateofAnalysis/ProductDatasheet

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