Description

Methoxy PEG Succinimidyl Carboxymethyl Ester for amine PEGylation, with superior quality specification of ≥95% Substitution.

JenKem Technology’s Methoxy PEG Succinimidyl Carboxymethyl Ester (Methoxy PEG NHS, MPEG NHS, MPEG SCM, or Methoxy PEG SCM) is a high quality amine reactive PEG product with a stable non-degradable linker between the PEG polymeric chain and the NHS ester. Methoxy PEG Succinimidyl Carboxymethyl Ester reacts with the amine group of lysine(s) at room temperature in less than 1hr at pH 7-8. Shorter hydrolysis half life of M-PEG-SCM ensures maximum selectivity towards most sterically available amine groups.

JenKem Technology offers Methoxy PEG SCM Ester with MW 2kDa (M-SCM-2000), MW 3kDa (M-SCM-3000), MW 5kDa (M-SCM-5000), MW 10kDa (M-SCM-10K), MW 20kDa (M-SCM-20K), MW 30 kDa (M-SCM-30K), MW 35 kDa (M-SCM-35K) and MW 40kDa (M-SCM-40K), in 1g and 10g packing sizes. Different MW of Methoxy PEG SCM Ester products may be available by custom synthesis, please email us at tech@jenkemusa.com for details on custom PEGs. Other linear NHS esters are available – please select other stable linker NHS PEGs, or cleavable linker NHS PEGs. JenKem Technology provides repackaging services for an additional fee, please contact us if you require a different package size than our catalog selection.

Bulk PEGs and GMP grade PEGs are made-to-order. Please contact us for bulk pricing.

Click here to download the MSDS

References:

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Founded in 2001 by experts in PEG synthesis and PEGylation, JenKem Technology specializes exclusively in the development and manufacturing of high quality polyethylene glycol (PEG) products and derivatives, and related custom synthesis and PEGylation services. JenKem Technology is ISO 9001 and ISO 13485 certified, and adheres to ICH Q7A guidelines for GMP manufacture. The production of JenKem® PEGs is back-integrated to in-house polymerization directly from ethylene oxide, enabling facile traceability for regulated customers. JenKem Technology caters to the PEGylation needs of the pharmaceutical, biotechnology, medical device and diagnostics, and emerging chemical specialty markets, from laboratory scale through large commercial scale.