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AG Scientific/Cycloheximide/C-1189/25 g

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C-1189-25g

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Cycloheximideisanantibioticactiveagainstmanyyeastsandfungi.Inhibitsproteinsynthesisineukaryotes(butnotinprokaryotes)byinterferingwiththetranslocationstep.Itinhibitschaininitiationaswellaschainelongationbyactingonthe60Ssubunitoftheeukaryoteribosome,interactingdirectlywithenzymetranslocase.Cycloheximideisusedasaninhibitortostudycell-freeproteinbiosynthesisineukaryotesandalsousedtoblockribosome-dependentinvivopolypeptidesynthesis.Itinducesapoptosisinavarietyofcells,butcanalsodelayorinhibitapoptosisbyotheragents.Cycloheximide’s longstandingapplicationasageneselectionantibiotic hasapowerfulnewroleinGenomeeditingutilizingtheCRISPR/Cas9system. ACandidaalbicansCRISPRsystempermitsgeneticengineeringofessentialgenesandgenefamilies.Cycloheximideisinstock.Callforbulkquotations,typicalleadforsuBDivision,packingandshippinglargerquantitiesis7-14days.Researchsizeorder100mg250mgleadisshorter.InternationalShippingofthismaterialcanbesubjecttoanadditionalhazardousshippingfee. AdditionalInformationSynonymsActidione,NaramycinA,NSC-185,U-4527Product#C-1189CAS#66-81-9ChemicalName4-[(2R)-2-[(1S,3S,5S)-3,5-DIMETHYL-2-OXOCYCLOHEXYL]-2-HYDROXYETHYL]PIPERIDINE-2,6-DIONEFormulaC15H23NO4MW281.3AppearanceWhiteSolidPurity95%SolubilitySolubleinChloroform,EthanolandMethanol.BoilingPoint491.8±10.0°Cat760mmHgPreparationStoresolutionsat-20°CStorageTemp+4°CTherapeuticAreaInfectiousDiseasesUseCycloheximideisahighlyeffectiveantibioticwithactivityagainstmold,yeast,andphytopathogenicfungi,withloweractivityagainstbacteriaAdditionalInformationMDLNumberMFCD00082346ChemACXX1006248-5InChIInChI=1S/C15H23NO4/c1-8-3-9(2)15(20)11(4-8)12(17)5-10-6-13(18)16-14(19)7-10/h8-12,17H,3-7H2,1-2H3,(H,16,18,19)/t8-,9-,11-,12+/m0/s1SMILESC[C@H]1C[C@@H](C(=O)[C@@H](C1)[C@@H](CC2CC(=O)NC(=O)C2)O)CdecorateTable("product-attribute-specs-table")

AG Scientific, Inc.成立于1997年，专注于创新生化制剂以及用于诊断测试开发的定制原材料，以推进临床前研究药物开发。产品涉及抗生素，生物洗涤剂，缓冲液，诊断，酶，医疗设备试剂，蛋白酶K，还原剂，RNase A等。