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AG Scientific/Hygromycin B in DI Water/H-1012-DI/1x10 ml
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HygromycinBisanaminoglycosideantibioticisolatedfrom Streptomyceshygroscopicus.Itiscommonlyusedtostudyproteinsynthesis.Asidefromitsefficacyagainstbacteria,fungi,andhighereukaryoticcells,hygromycinBisalsoanantiviralagentinhibitingtranslationuponselectivelyenteringcellsmadepermeableduetoviralinfection.Itworksasastandardselectionantibioticingeneexperiments,especiallyforselectionofhygromycinresistancegenetransformedcells.Aminoglycosideantibioticsarecomposedofaminogroupsattachedtoglycosides.Theybindthe30sribosomalsubunit,causingmisreADIngofthemRNAsequenceandinhibitionoftranslocation.Consequently,proteinsynthesisisinhibited.AntibioticsareoftenusedinclinicalinvitrotestsknownasantimicrobialsusceptibilitytestsorASTstodeterminetheirefficacyagainstcertainbacterialspecies. Hygromycin"s longstandingapplicationasageneselectionantibiotic,hasapowerfulnewroleinGenomeeditingutilizingtheCRISPR/Cas9system*ATTENTION!Internationalshippingofthismaterialcanbesubjecttoanadditionalhazardousshippingfee.AnAGScientificcustomerservicerepresentativewillcontactyoutoconfirmcostpriortoshippingyourinternationalorder. AdditionalInformationProduct#H-1012-DICAS#31282-04-9ChemicalNameO-6-Amino-6-deoxy-L-glycero-D-galacto-heptopyranosylidene-(1-2-3)-O-β-D-talopyranosyl(1-5)-2-deoxy-N3-methyl-D-streptamineFormulaC20H37N3O13MW527.53AppearanceSolution(100mg/mlinDIWater)Purity>95%SolubilitySolubleinWaterBoilingPoint897.6±65.0°Cat760mmHgPreparationWorkingsolutions(StorageTemp+4°CTherapeuticAreaInfectiousDiseasesUseHygromycinBisanantibioticproducedbythebacteriumStreptomyceshygroscopicus.Itisanaminoglycosidethatkillsbacteria,fungiAdditionalInformationMerckIndex13.4878MDLNumberMFCD06795479ChemACXX1009739-3InChIInChI=1S/C20H37N3O13/c1-23-7-2-5(21)9(26)15(10(7)27)33-19-17-16(11(28)8(4-25)32-19)35-20(36-17)18(31)13(30)12(29)14(34-20)6(22)3-24/h5-19,23-31H,2-4,21-22H2,1H3/t5-,6+,7+,8-,9+,10-,11+,12-,13-,14-,15-,16+,17+,18-,19+,20?/m1/s1SMILESCN[C@H]1C[C@H]([C@@H]([C@H]([C@@H]1O)O[C@H]2[C@@H]3[C@H]([C@H]([C@H](O2)CO)O)OC4(O3)[C@@H]([C@@H]([C@H]([C@H](O4)[C@H](CO)N)O)O)O)O)NdecorateTable("product-attribute-specs-table")
AG Scientific, Inc.成立于1997年,专注于创新生化制剂以及用于诊断测试开发的定制原材料,以推进临床前研究药物开发。产品涉及抗生素,生物洗涤剂,缓冲液,诊断,酶,医疗设备试剂,蛋白酶K,还原剂,RNase A等。
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