首页 > AG Scientific > AG Scientific/ETYA, eicosatetraynoic acid/E-2000/5 mg

提醒：代购产品，无质量问题不接受退换货，下单前请仔细核对信息。下单后请及时联系客服核对商品价格，订单生效后再付款。

AG Scientific/ETYA, eicosatetraynoic acid/E-2000/5 mg

价格：

登录查看

自营商城

解放采购

正品保障

及时交付

厂家直采

一站服务

货号：

E-2000-5mg

品牌：

AG Scientific

会员服务：

尊享会员价

贵宾专线

运费优惠

闪电退款

福利优惠

上门换新

友情提示

以上价格仅为参考，请联系客服询价。

免费咨询热线

4000-520-616

产品说明

Theperoxisomeproliferator-activatedreceptor(PPAR)-αactivator,5,8,11,14-eicosatetraynoicacid(ETYA),isanarachidonicacidanalog.Itisreportedtoinhibitup-regulationofpro-inflammatorygenes.Amongtheinflammatorychemokineselaborated,glialcell-derivedCCL2/MCP-1iscrucial,itpromotesthemigrationandrecruitmentofinflammatorycells,itisprimarilyresponsIBLefortheinitiationandprogressionofinflammatoryresponsesinneurodegenerativediseaseandalsoassociatedwithavarietyofdisease,includingatherosclerosis.ETYAhasananti-inflammatorymechanism,byincreasingHuR-mediated-MKP-1mRNAstABIlitythatleadstothespecificsuppressionofCCL2/MCP-1duringinflammatoryprocesses.StudieshaveshownthatETYAincreasesMKP-1expressionthroughHuRatthepost-transcriptionallevelinareceptor-independentmanner. TherebyprovidingevidencethatETYAisapotentialtherapeuticmodulatorofinflammation.ETYA"sinfluenceon suppressingCCL2/MCP-1expressionisanemergingtherapeuticstrategyforthetreatmentofneurodegenerativediseasessuchas Alzheimer"sdisease,multiplesclerosis,andbrainischemia.Arecentresearchregardingupperaerodigestivecancer(anaggressivemalignancy)hasrevealedthatPPARγpathwayswouldbeanoveltherapyforthiscancer.ETYAisaPPARγactivatorandresultsfromthisstudyhaveshownthatitdownregulatescellproliferationandhasantineoplasticfeatures. AdditionalInformationSynonymsEicosatetraynoicacid;5,8,11,14-EicosatetraynoicacidProduct#E-2000CAS#1191-85-1ChemicalNameOctadehydroarachidonicacid,EicosatetraynoicacidFormulaC20H24O2MW296.5AppearanceOffWhitetoWhiteSolidPurity≥98%SolubilitySolubleinethanol,methanol,orDMSO.StorageTemp+4°CAdditionalInformationdecorateTable("product-attribute-specs-table")

AG Scientific, Inc.成立于1997年，专注于创新生化制剂以及用于诊断测试开发的定制原材料，以推进临床前研究药物开发。产品涉及抗生素，生物洗涤剂，缓冲液，诊断，酶，医疗设备试剂，蛋白酶K，还原剂，RNase A等。