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Novus/Recombinant Human/Mouse/Rat Activin A Protein/338-AC-500

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338-AC-500

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Additional InformationCHO derivedDetails of FunctionalityMeasured by its ability to induce hemoglobin expression in K562 human chronic myelogenous leukemia cells. Schwall, R.H. et al. (1991) Method Enzymol. 198:340. The ED50 for this effect is 0.2‑1.2ng/mL.The specific activity of Recombinant Human/Mouse/Rat Activin A is approximately 1 IU/μg, which is calibrated against human ActivinA WHOInternational Standard (NIBSC code: 91/626).SourceChinese Hamster Ovary cell line, CHO-derived Activin A proteinGly311-Ser426Accession #P08476N-terminal SequenceGly311Structure / FormDisulfide-linked homodimer Protein/Peptide TypeRecombinant ProteinsGeneINHBAPurity>95%, by SDS-PAGE with silver staining.Endotoxin NoteTheoretical MW13 kDa (monomer). Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.SDS-PAGE14 kDa, reducing conditions24 kDa, non-reducing conditionsPublicationsReadPublications using 338-AC in the following applications: Bioassay 317 publications Cell Culture 22 publications Differentiation 4 publications ELISA (Standard) 1 publication Flow Cytometry 1 publication In Vivo 6 publications Stimulation 1 publication Surface Plasmon Resonance 2 publications

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