Summary:StandardCurveRange0.31ng/ml-20ng/mLSensitivityTheminimumdetectabledoseofhumanInterleukin-17wasdeterminedtobeapproximately1ng/mlAssayTypeSandwichELISASampleVolume100uLKitTypeELISAKit(Colorimetric)GeneIL17AApplications/Dilutions:ApplicationNotesThehumanIL17ELISAkitisforquantitativedeterminationofIL17concentrationsinhumancellculturesupernatantsandBIOLOGicalfluids(plasma,serum).Thiskitisforresearchpurposeonly.PublicationsReadPublicationusingDDXK-E-IL17A.Packaging,Storage&Formulations:ComponentsDetectionAntibody:0.5mg/mLofHRPO-conjugatedanti-IL17mousemonoclonalantibody(clone405B4.01).Dilutetoaworkingconcentrationof3ug/mLinPBS-BSA1%-Tween0.05%.Standard:Eachvialcontains1ug/mLofrecombinantIL17produced,purifiedandconcentratedfromeukaryoticcells.A7-pointstandardcurveusing2-foldserialdilutionsinsampledilutionbuffer,andahighstandardof20ng/mLisrecommendedCaptureAntibody:0.5mg/mLofmouseanti-IL17monoclonalantibody(clone408H6.01).Dilutein50mMcarbonatebufferpH9.6toaworkingconcentrationof2.5ug/mLNotes:ThisproductismanufacturedbyDendriticsanddistributedbyNovusBiologicalsinNorthAmericaandotherselectcountries.Toorderinthefollowingcountries:Germany,Finland,UnitedKingdom,Norway,Denmark,Switzerland,AustriaandSouthKorea,pleasecontactDendriticsforadditionalorderinginformation.AlternateNamesfor53BP1Antibody:CTLA-8CTLA8cytotoxicT-lymphocyte-associatedserineesterase8CytotoxicT-lymphocyte-associatedantigen8IL17IL-17IL17AIL-17AIL-17AcytotoxicT-lymphocyte-associatedprotein8IL-17CTLA-8IL17interleukin-17Ainterleukin17(cytotoxicT-lymphocyte-associatedserineesterase8)interleukin17ABackground:IL17(cytotoxicTlymphocyteassociatedantigen8)isaCD4+Tcell-derivedcytokinethatstimulatesstromalcellsandmacrophagestosecreteproinflammatorycytokines.IL17regulatestheactivitiesofNF-kappaBandmitogen-activatedproteinkinases.hIL17stimulatesepithelial,endothelial,andfibroblasticcellstosecretecytokinessuchasIL6,IL8,andG-CSFandPGE2.IL17promotedthematurationofDCProgenitors,asevidencedbyincreasedcellsurfaceexpressionofcostimulatorymoleculesandMHCclassIIAg,andallostimulatorycapacity.IL17hadalessereffectonthephenotypeandfunctionofmorefullydifferentiatedmyeloidDC.ThesefindingssuggestaroleforIL17inallogeneicTcellproliferationthatmaybemediatedinpartviaamaturation-inducingeffectonDC.IL17appearstobeanoveltargetfortherapeuticinterventioninallograftrejection.Highlevelsofthiscytokineareassociatedwithseveralchronicinflammatorydiseasesincludingrheumatoidarthritis,psoriasisandmultiplesclerosis.(FossiezF.etal,1996;J.Exp.Med,183:2593-2603;FossiezF.etal,1998;Int.Rev.Immunol.,16:541-551).Limitations:CTLA-8CTLA8cytotoxicT-lymphocyte-associatedserineesterase8CytotoxicT-lymphocyte-associatedantigen8IL17IL-17IL17AIL-17AIL-17AcytotoxicT-lymphocyte-associatedprotein8IL-17CTLA-8IL17interleukin-17Ainterleukin17(cytotoxicT-lymphocyte-associatedserineesterase8)interleukin17A

 

点击授权经销商名单，订购品质保障产品。

 

Novus抗体		Novus蛋白		Valukine™ ELISA试剂盒
33,000+产品引用文献 3,000+产品客户五星推荐 200,000产品应用数据 9,000+小包装抗体   点击查看抗体产品		高生物活性 高纯度 超低内毒素水平 批次之间非常稳定   点击查看蛋白产品		产品源自美国 专供中国市场 保证准确性、灵敏度、重复性和特异性 点击查看Valukine™ ELISA产品

 

Novus Biologicals，抗体一站式服务专家。
作为世界上最大的抗体生产商，Novus Biologicals 携近16万种抗体席卷而来，完美解决您的需求。

奖励计划

Novus产品评价奖励计划：即日起，Novus奖励计划将不需要累积积分，即可直接获得亚马逊礼物卡。具体新计划详情请点击此海报。 文献奖励计划：您使用Novus的产品发表过文章吗？把您的发表信息提供给我们，即可换取价值￥300或￥600的亚马逊卡。 奖励计划中文细则，请点击此处。

 

创新奖励计划，你验证，我买单

提交所购买一抗尚未验证的物种或应用数据，奖励所购买一抗价格等值抵用券

创新奖励计划，如何获得抵用券 向我司授权代理商索取创新奖励抗体申请表 填写图片、实验步骤和结果说明等信息，提交到techsupport.cn@bio-techne.com 核实图片、实验步骤和结果说明 信息确认后，我司通过邮件发送与您所购买产品价格等值抵用券 抵用券仅适用于Novus Biologicals的一抗产品，具体细则，详见抵用券上的说明 注：参加创新奖励，请登录Novus官网一抗页面，在species 和tested application选项确认验证的物种或应用不在列表中