首页 > Usbio > Usbio/14-3-3 eta, Recombinant, Human, aa1-246, His-Tag (Tyrosine 3-monooxygenase/100ug/351042

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Usbio/14-3-3 eta, Recombinant, Human, aa1-246, His-Tag (Tyrosine 3-monooxygenase/100ug/351042

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The 14-3-3 family of proteins plays a key regulatory role in signal transduction, checkpoint control, apoptotic and nutrient-sensing pathways. 14-3-3 proteins are highly conserved and ubiquitously expressed. There are at least seven isoforms, beta, gamma, epsilon, sigma, zeta, tau and eta that have been identified in mammals. The 14-3-3 eta, a subtype of the 14-3-3 family of proteins, was found in B cells, brain, cerebrospinal fluid etc. 14-3-3 eta interacts with and relocalizes the A20 zinc finger protein from the insoluble to the soluble fraction, suggesting a chaperone function. ||Source:|Recombinant protein corresponding to aa1-246 from human 14-3-3 eta, fused to His-tag at N-terminal expressed in E. coli.||Molecular Weight: |~30.3kD (266aa)||AA Sequence:|MGSSHHHHHH SSGLVPRGSH MGDREQLLQR ARLAEQAERY DDMASAMKAV TELNEPLSNE DRNLLSVAYK NVVGARRSSW RVISSIEQKT MADGNEKKLE KVKAYREKIE KELETVCNDV LSLLDKFLIK NCNDFQYESK VFYLKMKGDY YRYLAEVASG EKKNSVVEAS EAAYKEAFEI SKEQMQPTHP IRLGLALNFS VFYYEIQNAP EQACLLAKQA FDDAIAELDT LNEDSYKDST LIMQLLRDNL TLWTSDQQDE EAGEGN||Storage and Stability:|May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.Source: Recombinant, human from E. coli|Purity: ~95% (SDS-PAGE)|Concentration: ~1mg/ml |Form: Supplied as a liquid in 20mM Tris, pH 8.0, 10% glycerol.||Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.

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