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Usbio/Hepcidin, Recombinant, Larimichthys Crocea, aa65-85 (Hamp)/10ug/405941
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Seemstoactasasignalingmoleculeinvolvedinthemaintenanceofironhomeostasis.SeemstoberequiredinconjunctionwithHFEtoregulatebothintestinalironabsorptionandironstorageinmacrophagesHasverystrongantibacterialactivityagainstthemarineGram-negativebacteriaV.alginolyticus(MIC=24uM),V.fluvialis,V.harveyis(MIC=12uM)andV.parahaemolyticus(MIC=6uM).HasantibacterialactivityagainsttheGram-negativebacteriaA.hydrophila(MIC=6uM),E.coli(MIC=24uM),andE.coliBL21(DE3)plysS(MIC=6uM),andtheGram-positivebacteriaB.cereus(MIC=24uM),B.subtilis(MIC=6uM),C.glutamicum(MIC=3uM),M.luteus(MIC=3uM),M.lysodeikticus,S.aureus(MIC=6uM)andS.epidermis(MIC=12uM).PossessesantifungalactivityagainstA.niger(MIC=24uM),F.graminearum(MIC=24uM)andF.solani(MIC=24uM),butlacksantifungalactivityagainsttheyeastsP.pastorisGS115andC.albicans.||Source:|Recombinantproteincorrespondingtoaa65-85fromlarimichthyscroceaHepcidin,expressedinE.coli.||MolecularWeight:|~2.5kD||AASequence:|RCRFCCRCCPRMRGCGICCRF||StorageandStABIlity:|Maybestoredat4°Cforshort-termonly.Aliquottoavoidrepeatedfreezingandthawing.Storeat-20°C.Aliquotsarestablefor6monthsafterreceiptat-20°C.Formaximumrecoveryofproduct,centrifugetheoriginalvialafterthawingandpriortoremovingthecap.Furtherdilutionscanbemadeinassaybuffer.ImportantNote:Thisproductassuppliedisintendedforresearchuseonly,notforuseinhuman,therapeuticordiagnosticapplicationswithouttheexpressedwrittenauthorizationofUnitedStatesBIOLOGical.ToxicityandHazards: Allproductsshouldbehandledbyqualifiedpersonnelonly,trainedinlaboratoryprocedures.

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