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Usbio/484104 Rabbit Anti-KDM4B/484104/100ul

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KDM4B is a histone demethylase that specifically demethylates 'Lys- 9' of histone H3, thereby playing a role in histone code. It does not demethylate histone H3 'Lys-4', H3 'Lys-27', H3 'Lys-36' nor H4 'Lys-20'. Only able to demethylate trimethylated H3 'Lys-9', with a weaker activity than KDM4A, KDM4C and KDM4D. Demethylation of Lys residue generates formaldehyde and succinate.Applications: |Suitable for use in Western Blot. Other applications not tested.Recommended DilutionOptimal dilutions to be determined by the researcher.Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.ImmunogenSynthetic peptide corresponding to the N-terminal region of Human KDM4BFormSupplied as a liquid in PBS, 2% sucrose, 0.09% sodium azide.PurityPurified by affinity chromatography.SpecificityRecognizes human KDM4B.

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