MaxLight™550 is a new Yellow-Green photostable dye conjugate comparable to Alexa Fluor™546, 555, DyLight™549 , Cy3™, TRITC and offers better labeling efficiency, brighter imaging and increased immunodetection. Absorbance (550nm); Emission (575nm); Extinction Coefficient 150,000.Plasmodium vivax is a protozoan parasite that causes malaria in humans. Malaria caused by P. vivax is seldom lethal but is the most common outside sub-Saharan Africa. The parasite is transmitted by Anopheles mosquitoes. Merozoites are the result of asexual reproduction of the parasite in the hepatocytes. They are released from hepatocytes and infected erythrocytes to infect other erythrocytes. MSP1 is the most abundant protein on the surface of merozoites and is involved in parasite invasion of the erythrocyte. It has long been considered a promising candidate for a vaccine against malaria. Some studies have shown that naturally acquired antibodies to a cleavage product of MSP1 can be linked to a reduced risk of clinical malaria.ApplicationsSuitable for use in FLISA and Western Blot. Other applications not tested.Recommended DilutionOptimal dilutions to be determined by the researcher.Hybridoma: |Sp2/0 myeloma cells with spleen cells from Balb/c mice.Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.Note: Applications are based on unconjugated antibody.ImmunogenPlasmodium vivax MSP1.FormSupplied as a liquid in PBS, pH 7.2. Labeled with MaxLight™550.PurityPurified by Protein G affinity chromatography.SpecificityRecognizes the merozoite surface protein 1 (MSP1) of Plasmodium vivax.

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