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Usbio/252967-Biotin Mouse Anti-TREX1 (Three Prime Repair Exonuclease 1, AGS1, AGS5, CRV, DKFZp434J0310, DRN3, HERNS) (Biotin)/252967-Biotin/100ul
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产品说明
This gene encodes the major 3'->5' DNA exonuclease in human cells. The protein is a non-processive exonuclease that may serve a proofreading function for a human DNA polymerase. It is also a component of the SET complex, and acts to rapidly degrade 3' ends of nicked DNA during granzyme A-mediated cell death. Mutations in this gene result in Aicardi-Goutieres syndrome, chilblain lupus, and Cree encephalitis. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq.Applications: |Suitable for use in ELISA, Western Blot. Other applications not tested.Recommended DilutionOptimal dilutions to be determined by the researcher.AA SequenceMGPGARRQGRIVQGRPEMCFCPPPTPLPPLRILTLGTHTPTPCSSPGSAAGTYPTMGSQALPPGPMQTLIFFDMEATGLPFSQPKVTELCLLAVHRCALEStorage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Note: Applications are based on unconjugated antibody.ImmunogenTREX1 (NP_057465, 1aa-100aa) partial recombinant protein with GST tag. MW of the GST tag alone is 26kD.FormSupplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with Biotin.PurityPurifiedSpecificityRecognizes TREX1.

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