首页 > Usbio > 207469-AF555 Mouse Anti-ACVRL1 (Activin A Receptor Type II-like 1, TGF-B Superfamily Receptor Type I, Activin A Receptor, Type II-like Kinase 1, Serine/Threonine-Protein Kinase Receptor R3, ACVRLK1, ALK-1, ALK1, HHT, HHT2, ORW2, SKR3, TSR-I) (AlexaFluor&r

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207469-AF555 Mouse Anti-ACVRL1 (Activin A Receptor Type II-like 1, TGF-B Superfamily Receptor Type I, Activin A Receptor, Type II-like Kinase 1, Serine/Threonine-Protein Kinase Receptor R3, ACVRLK1, ALK-1, ALK1, HHT, HHT2, ORW2, SKR3, TSR-I) (AlexaFluor&r

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207469-AF555

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This gene encodes a type I cell-surface receptor for the TGF-beta superfamily of ligands. It shares with other type I receptors a high degree of similarity in serine-threonine kinase subdomains, a glycine- and serine-rich region (called the GS domain) preceding the kinase domain, and a short C-terminal tail. The encoded protein, sometimes termed ALK1, shares similar domain structures with other closely related ALK or activin receptor-like kinase proteins that form a subfamily of receptor serine/threonine kinases. Mutations in this gene are associated with hemorrhagic telangiectasia type 2, also known as Rendu-Osler-Weber syndrome 2. Applications: |Suitable for use in ELISA and Western Blot. Other applications not tested.Recommended DilutionOptimal dilutions to be determined by the researcher.AA SequenceDPVKPSRGPLVTCTCESPHCKGPTCRGAWCTVVLVREEGRHPQEHRGCGNLHRELCRGRPTEFVNHYCCDSHLCNHNVSLVLEATQPPSEQPGTDGQLStorage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.ImmunogenRecombinant protein corresponding to aa22-119 from human ACVRL1 with GST tag. MW of the GST tag alone is 26kD.FormSupplied as a liquid in PBS, pH 7.2.PurityPurifiedSpecificityRecognizes human ACVRL1.

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