产品说明
This gene encodes a protein that is a member of the dickkopf family. It is a secreted protein with two cysteine rich regions and is involved in embryonic development through its inhibition of the WNT signaling pathway. Elevated levels of DKK1 in bone marrow plasma and peripheral blood is associated with the presence of osteolytic bone lesions in patients with multiple myeloma. [provided by RefSeqApplications: |Suitable for use in Western Blot. Other applications not tested.Recommended DilutionOptimal dilutions to be determined by the researcher.AA SequenceQPYPCAEDEECGTDEYCASPTRGGDAGVQICLACRKRRKRCMRHAMCCPGNYCKNGICVSSDQNHFRGEIEETITESFGNDHSTLDGYSRRTTLSSKMYHStorage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.ImmunogenDKK1 (NP_036374, 81aa-180aa) partial recombinant protein with GST tag. MW of the GST tag alone is 26kD.FormSupplied as a liquid in PBS, pH 7.4.PurityPurifiedSpecificityRecognizes human DKK1.
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