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Usbio/123863-ML550 Rabbit Anti-BCAP31 (B Cell Receptor-associated Protein 31, BCR-associated Protein 31, Bap31, 6C6-AG Tumor-associated Antigen, Protein CDM, P28, BAP31, DXS1357E) (MaxLight 550)/123863-ML550/100ul
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MaxLight™550isanewYellow-GreenphotostabledyeconjugatecomparabletoAlexaFluor™546,555,DyLight™549,Cy3™,TRITCandoffersbetterlabelingefficiency,brighterimagingandincreasedimmunodetection.Absorbance(550nm);Emission(575nm);ExtinctionCoefficient150,000.BAP31appearstobeamulti-functionalER-associatedtransportproteinwhichwasoriginallyidentifiedthroughitsassociationwithmembraneIgDinBlymphocytes.SeveralproteinshavesincebeenshowntoassociatewithBAP31,includingtheBeta2integrinreceptorCD11b/CD18,andnonmusclegamma-actinandmyosinBheavychain.BAP31hasbecomeafocusareaforapoptosisstudiesduetoitsassociationwithBcl-2andcleavagebyinitiatorcaspasesincludingcaspase1and8.CleavageofBAP31generatesamembrane-integratedp20fragmentwhichisitselfapotentinducerofapoptosiswhenexpressedectopically.ApplicationsSuitableforuseinWesternBlot.Otherapplicationsnottested.RecommendedDilutionOptimaldilutionstobedeterminedbytheresearcher.AASequenceMSLQWTAVATFLYAEVFVVLLLCIPFISPKRWQKIFKSRLVELLVSYGNTFFVVLIVILVLLVIDAVREIRKYDDVTEKVNLQNNPGAMEHFHMKLFRAQRNLYIAGFSLLLSFLLRRLVTLISQQATLLASNEAFKKQAESASEAAKKYMEENDQLKKGAAVDGGKLDVGNAEVKLEEENRSLKADLQKLKDELASTKQKLEKAENQVLAMRKQSEGLTKEYDRLLEEHAKLQAAVDGPMDKKEEStorageandStABIlityMaybestoredat4°Cforshort-termonly.Aliquottoavoidrepeatedfreezingandthawing.Storeat-20°C.Aliquotsarestableforatleast12months.Formaximumrecoveryofproduct,centrifugetheoriginalvialafterthawingandpriortoremovingthecap.Note:Applicationsarebasedonunconjugatedantibody.

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