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038514-ML550 Rabbit Anti-MMRN1, NT (MMRN1, ECM, EMILIN4, GPIA*, MMRN, Multimerin-1, EMILIN-4, Elastin Microfibril Interface Located Protein 4, Endothelial Cell Multimerin, Platelet Glycoprotein Ia*, 155kD Platelet Multimerin) (MaxLight 550)
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MaxLight™550 is a new Yellow-Green photostable dye conjugate comparable to Alexa Fluor™546, 555, DyLight™549 , Cy3™, TRITC and offers better labeling efficiency, brighter imaging and increased immunodetection. Absorbance (550nm); Emission (575nm); Extinction Coefficient 150,000. Multimerin is a massive, soluble protein found in platelets and in the endothelium of blood vessels. It is comprised of subunits linked by interchain disulfide bonds to form large, variably sized homomultimers. Multimerin is a factor V/Va-binding protein and may function as a carrier protein for platelet factor V. It may also have functions as an extracellular matrix or adhesive protein. Recently, patients with an unusual autosomal-dominant bleeding disorder (factor V Quebec) were found to have a deficiency of platelet multimerin.ApplicationsSuitable for use in Western Blot and FLISA. Other applications not tested.Recommended DilutionsOptimal dilutions to be determined by the researcher.Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.Note: Applications are based on unconjugated antibody.References1. Davila, S., et al. Genes Immun. 11(3):232-238(2010). 2. Simon-Sanchez, J., et al. Nat. Genet. 41(12):1308-1312(2009). 3. Tasneem, S., et al. J. Thromb. Haemost. 7(4):685-692(2009). 4. Jeimy, S.B., et al. Thromb. Haemost. 100(6):1058-1067(2008). 5. Jeimy, S.B., et al. Thromb. Res. 123(2):352-354(2008)
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