Species: Human Host Species: Sf9 insect cells MW: 251 kDa (complex) Genbank #: NM_002649 (p110γ), NM_001142633 (PIK3R5) Tag(s): N-terminal His-tag (p110γ), N-terminal GST-tag (PIK3R5) a.a: PIK3CG 2–1102 (end), PIK3R5 2–880 (end) Description:Complex of N-terminal His-tag recombinant human p110γ (PIK3CG), (GenBank Accession No. NM_002649) a.a. 2-1102 (end), and N-terminal GST-tag recombinant human PIK3R5 (GenBank Accession No. NM_001142633) a.a. 2 -880 (end). Co-expressed in a Baculovirus infected Sf9 cell expression system. p110 MW=127 kDa, PIK3R5 MW=124 kDa. Synonym(s): PIK3CG, p110gamma, PIK3R5, phosphoinositide-3-kinase, regulatory subunit 5, FOAP2 Formulation: 40 mM Tris-HCl, pH 8.0, 110 mM NaCl, 2.2 mM KCl, 16 mM glutathione, 3 mM DTT, 20% glycerol. Format: Aqueous buffer solution Storage / Stability: >
6 months at –80°C Application(s): Useful for the study of enzyme kinetics, screening inhibitors, and selectivity profiling. Reference(s): 1. Shymanets, A. et al., Biochem. J. 2012 Feb 1,441(3): 851-8. 2. Brazzatti, J.A., et al., Oncogene. 2012 May 3,31(18):2350-61. Warning(s): Avoid freeze/thaw cycles Scientific Category: Kinase/Lipids Product Type: Recombinant Protein Data shown is lot-specific. Contact us for specific information on other lots.