News Events .sub-menu\" data-toggle-type=\"slidetoggle\" data-toggle-duration=\"250\" aria-expanded=\"false\">Show sub menu News Events NanoFCM Deciphering Bio Nanoparticles Sizing，Concentration & Phenotyping Read More HIGH PERFORMANCE Ultra-Sensitive and High Resolution for both scatter and fluorescence. NO SWARM DETECTION Real time, single particle measurement LABEL FREE Direct size and concentration measurement without staining Flexible No proprietary reagents, choose from a vast array of commercially available markers EXTRACELLULAR VESICLES THE ORIGIN AND PHENOTYPING OF EXTRACELLULAR VESICLES VIRUSES TRULY QUANTITATIVE MEASUREMENT OF TOTAL TITER AND SUBGROUP TITER OF VIRUS NANOMEDICINE COMPREHENSIVE MEASUREMENT SUITE FOR NANOSIZED DRUG PRODUCTS BACTERIA TRULY QUANTITATIVE MEASUREMENT OF TOTAL BACTERIAL TITRE MITOCHONDRIA HIGH-THROUGHPUT MULTIPARAMETER ANALYSIS OF INDIVIDUAL MITOCHONDRIA NANOMATERIALS COMPREHENSIVE MEASUREMENT SUITE FOR NANOPARTICLES up to 12,000 particles/min Lower detection limit 7 nm (gold nanoparticles) to 40 nm (exosomes, viruses) High detection limit (1 micron) For many years scientists yearned for the possibility of performing flow cytometry to analyse small bio-nanoparticles that are too small to be measured by conventional and high sensitivity instruments. These entities, extracellular vesicles, gene therapy vectors, viruses and drug delivery particles, are promised to become the next generation of therapeutics, but they have been hard to handle and characterise due to their small size and biological or chemical heterogeneity. There is therefore a strong case for bringing flow cytometry capability to the sub-200nm scale. Innovation brings the solution NanoFCM has developed the NanoAnalyzer platform that now enables true flow-cytometry measurement at the sub-micron scale, and down to particle sizes unreachable by any other flow cytometers (10-40nm depending on the nature of the substrate). Nano-flow cytometry, the technology that underpins the NanoAnalyzer, removes bias and uncertainty stemming from the use of fluorescence signal triggering by using its highly sensitive side-scatter channel to trigger particle events. The single-particle nature of the measurement prevents uncontrolled swarming events, reinforcing data integrity. High resolution of both scatter and fluorescence channels allows the assessment of subpopulations, based on size or on bio-chemical properties. A new paradigm for bio-nanoparticle analysis Nano-flow cytometry’s ability to measure simultaneously a (bio)-nanoparticle population for size, size distribution and bio-chemical properties on a single instrument dramatically improves data quality and throughput compared to the traditional, multiple-techniques approach involving particle characterisation and counting (DLS, NTA, RPS), combined with chemical and biological function assessment (ELISA, Western Blot, Flow Cytometry, PCR). Quantitative measurement of the active and contaminant particles in a single preparation opens up the possibility of characterisation-based nanomedicine regulatory approval, and allows the conduct of large-scale clinical studies. From the research laboratory to the quality control department, NanoFCM delivers comprehensive bio-nano analysis. Read More SIZE DISTRIBUTION High-resolution size distribution comparable to TEM PARTICLE CONCENTRATION Measure the absolute concentration of both total particles and subpopulations Multiparameter Quantify sub-populations with up to 2 markers simultaneously Phenotyping Based on single -molecule fluorescence detection, Phenotype quantify direct from marker labeling intensity. NanoFCM DKSH Partnership Connect with the NanoFCM team at the ISEV (International Society for Extracellular Vesicles) 2021 virtual meeting, May 18-21 A Comprehensive Study on Single Extracellular Vesicles Single Extra Cellular phenotyping on the NanoAnalyzer platforms is used to evaluate the efficiency of four isolations techniques on three different media. NanoFCM at ISEV 2021 Connect with the NanoFCM team at the ISEV (International Society for Extracellular Vesicles) 2021 virtual meeting, May 18-21