Species: Human Host Species: HEK293 Cell MW: 52.8 kDa Genbank #: NM_014495.3 Tag(s): C-terminal FLAG-tag a.a: 1-460Description:Human angiopoietin-like 3(ANGPTL3 protein) also known as angiopoietin-relatedprotein 3, or angiopoietin 5 (Ang5),GenBank Accession No. NM_014495.3,a.a. 1-460 with a C-terminal FLAG tag,expressed in a HEK293 cell expressionsystem.UniProt Q9Y5C1Synonym(s): ANGPTL3 Protein, angiopoietin-related protein 3, angiopoietin 5, Ang5Purity: ≥
90% as determined by SDS-PAGEEndotoxin Level: <1 EU/µgBiological Activity: Angiopoietin-like 3activity was confirmed by treating THP-1cells with 500 ng/ml of angiopoietin-like 3for 15 min, 30 min, 2 hr, or 4 hr.Phosphorylated-Erk was measured byWestern blot and compared to total Erklevels.Formulation: Lyophilized powder from 8mM phosphate, pH 7.4, 100 mM NaCl, and2.2 mM KCl.Format: Aqueous buffer solutionStorage / Stability: >12 months at -80°CApplication(s): Useful for in vitro cell culture assays or in vivo applications.Reference(s):

1. Ando, Y., et al., J. Lipid Res. 44: 1216-1223.2. Lee, E-Chiang, et al., J. Biol. Chem. 284:13735-13745.

Scientific Category: CytokinesProduct Type: Recombinant ProteinData shown is lot-specific. Contact us for specific information on other lots.