Species: Human Host Species: HEK293 MW: 46.4 kDa Genbank #: BC_051271 Tag(s): C-terminal Fc fusion (Human IgG1) a.a: 73-253 Description:Secreted frizzled receptor (FZD1)-Fc fusionprotein and WNT receptor, also known asFZD1, GenBank Accession No.BC_051271,a.a. 73-253, expressed in a HEK293 cellexpression system. MW = 46.4 kDa(monomer). This protein runs at a higherapparent M.W. by SDS-PAGE due toglycosylation. UniProt Q9UP38 Synonym(s): FZD1 Formulation:

Sterile-filtered (0.2 µm) solution of 40 mM Tris, pH 8.0, 110 mM NaCl, 2.2 mM KCl, and 20% glycerol.

Format: Aqueous buffer solution Storage / Stability: At least 6 months at –80°C. Application(s): Useful for the study of enzyme kinetics, screening inhibitors, and selectivity profiling. Reference(s):

1. Moffat LL., et al., Development. 2014 Feb;141(3):617-28.

2. Surana, R., et al., Biochim Biopys Acta. 2014 Jan;1845(1):53-65.

Warning(s): Avoid freeze/thaw cycles. Scientific Category: Cell Surface Receptor Product Type: Recombinant Protein Data shown is lot-specific. Contact us for specific information on other lots.