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GenWay/17-α-OH Progesterone-ELISA Kit/GWB-19D810/96 TESTS
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Description:ProductName:Progesterone,17-aHydroxy-Category:FertilitySampleType:SerumSensitivity:0.05ng/mLDescription:Anunknownamountof17-a-OHPpresentinthesampleandafixedamountof17-a-OHPconjugatedwithhorse-rADIshperoxidasecompeteforbinding.Introduction:TheGenWay17-a-OHProgesteroneEnzymeImmunoassayKitprovidesmaterialsforthequantitativedeterminationof17-a-OHProgesteroneinserum.Thisassayisintendedforresearchuseonly.Thesteroid17-a-Hydroxyprogesterone(17-a-OHP)isproducedbyboththeadrenalcortexandgonads.Eventhough17-a-OHPhasrelativelylittleprogestationalactivity,itisofintenseclinicalinterestbecauseitistheimmediateprecursorto11-desoxycortisol(Cpd-S).BecauseCpd-Sisproducedby21-hyUroxytationof17-o-0HP,measurementof17--o-0HPisausefulindirectindicatorof21.hydroxylaseactivity.Incongenital21hydroxylasedeficiency,themostcommonvarietyofcongenitaladrenalhyperplasia(CAH),17-a-OHPissecretedinabundantexcess.Itismoderatelyelevatedinthe11-f!-hydroxylasedeficiencyaswell.Measurementof17-a-OHPisthereforevaluableintheinitialdiagnosisofCAH.Principleofthetest:TheGenWay17-a-OHProgesteroneELISAKitisasolidphaseenzyme-linkedimmunosorbentassay(ELISA),basedontheprincipleofcompetitivebinding.Themicrotite-wellsarecoatedwithapoIyclonalantibodydirectedtowardsanantigenicsiteonthe17-a-OHPmolecule.Endogenous17-a-OHPofapatientsamplecompeteswitha17-a-OHP-horseradishperoxidaseconjugateforbindingtothecoatedantibody.Afterincubationtheunboundconjugateiswashedoff.Theamountofboundperoxidaseconjugateisinverselyproportionaltotheconcentrationof17-a-OHPinthesample.Afteradditionofthesubstratesolution,theintensityofcolordevelopedisinverselyproportionaltotheconcentrationof17-a-OHPinthepatientsample.StorageandStABIlity:Whenstoredat2-8Cunopenedreagentswillretainreactivityuntilexpirationdate.Donotusereagentsbeyondthisdate.Openedreagentsmustbestoredat2-8C.Microtiterwellsmustbestoredat2-8C.Oncethefoilbaghasbeenopened,careshouldbetakentoclosetightlyagain.Openedkitsretainactivityforsixweeksifstoredasdescribedabove.ProductName:Progesterone,17aHydroxy-AdditionalInformation:Name17-α-OHProgesterone-ELISAKitRelatedProductNamesProgesterone.17aHydroxy-ELISAKitProgesterone,17aHydroxy-IntendedUseResearchUseOnly

GenWay生物科技是一家领先的蛋白质和抗体解决方案供应商。自1998年以来,他们已经提供蛋白质的解决方案和应用研究。迄今为止,GenWay生物科技的在圣地亚哥工厂产生了数以千计的蛋白质和抗体。公司致力于为客户提供研究界最好的试剂。如果产品不符合既定的规格,公司将全额退款。

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