首页 > Assay BioTech > Assay BioTech/NFκB-p105 Antibody/100 μl/B0021

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Assay BioTech/NFκB-p105 Antibody/100 μl/B0021

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B0021

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DetailsProduct NameNFκB-p105 AntibodyDescriptionnuclear factor kappa B subunit 1(NFKB1) Homo sapiens This gene encodes a 105 kD protein which can undergo cotranslational processing by the 26S proteasome to produce a 50 kD protein. The 105 kD protein is a Rel protein-specific transcription inhibitor and the 50 kD protein is a DNA binding subunit of the NF-kappa-B (NFKB) Protein complex. NFKB is a transcription regulator that is activated by various intra- and extra-cellular stimuli such as cytokines, oxidant-free radicals, ultraviolet irradiation, and bacterial or viral products. Activated NFKB translocates into the nucleus and stimulates the expression of genes involved in a wide variety of biological functions. Inappropriate activation of NFKB has been associated with a number of inflammatory diseases while persistent inhibition of NFKB leads to inappropriate immune cell development or delayed cell growth. Alternative splicing results in multiple transcript variants encoding different isofCatalog NoB0021ReactivityHuman, MouseApplicationsWB, IHC-p, IF/ICC, ELISAModificationUnmodified/TotalSourcePolyclonal RabbitDilutionWestern Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/40000. Not yet tested in other applications.PurificationThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.Concentration1 mg/mlStorage and Stability-20°C/1 yearOther NameNFKB1; Nuclear factor NF-kappa-B p105 subunit; DNA-binding factor KBF1; EBP-1; Nuclear factor of kappa light polypeptide gene enhancer in B-cells 1Molecular Weight (Da)105356Gene NameNFKB1Protein NameNuclear factor NF-kappa-B p105 subunitHuman Gene ID4790Human Swiss Prot No.P19838ImmunogenThe antiserum was produced against synthesized peptide derived from human NF-kappaB p105/p50. AA range:896-945SpecificityNFκB-p105 Polyclonal Antibody detects endogenous levels of NFκB-p105 protein.FormulationLiquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

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