Angewandte Chemie International EditionVolume 50, Issue 16 p. 3751-3754 Communication Fluorogenic DNAzyme Probes as Bacterial Indicators† Dr. M. Monsur Ali, Department of Biochemistry and Biomedical Sciences and Department of Chemistry and Chemical Biology, McMaster University, 1200 Main Street West, Hamilton, Ontario, L8N 3Z5 (Canada), Fax: (+1) 905-522-9033Search for more papers by this authorSergio D. Aguirre, Department of Biochemistry and Biomedical Sciences and Department of Chemistry and Chemical Biology, McMaster University, 1200 Main Street West, Hamilton, Ontario, L8N 3Z5 (Canada), Fax: (+1) 905-522-9033Search for more papers by this authorDr. Hadeer Lazim, Department of Biochemistry and Biomedical Sciences and Department of Chemistry and Chemical Biology, McMaster University, 1200 Main Street West, Hamilton, Ontario, L8N 3Z5 (Canada), Fax: (+1) 905-522-9033Search for more papers by this authorProf. Dr. Yingfu Li, Corresponding Author liying@mcmaster.ca Department of Biochemistry and Biomedical Sciences and Department of Chemistry and Chemical Biology, McMaster University, 1200 Main Street West, Hamilton, Ontario, L8N 3Z5 (Canada), Fax: (+1) 905-522-9033Department of Biochemistry and Biomedical Sciences and Department of Chemistry and Chemical Biology, McMaster University, 1200 Main Street West, Hamilton, Ontario, L8N 3Z5 (Canada), Fax: (+1) 905-522-9033Search for more papers by this author Dr. M. Monsur Ali, Department of Biochemistry and Biomedical Sciences and Department of Chemistry and Chemical Biology, McMaster University, 1200 Main Street West, Hamilton, Ontario, L8N 3Z5 (Canada), Fax: (+1) 905-522-9033Search for more papers by this authorSergio D. Aguirre, Department of Biochemistry and Biomedical Sciences and Department of Chemistry and Chemical Biology, McMaster University, 1200 Main Street West, Hamilton, Ontario, L8N 3Z5 (Canada), Fax: (+1) 905-522-9033Search for more papers by this authorDr. Hadeer Lazim, Department of Biochemistry and Biomedical Sciences and Department of Chemistry and Chemical Biology, McMaster University, 1200 Main Street West, Hamilton, Ontario, L8N 3Z5 (Canada), Fax: (+1) 905-522-9033Search for more papers by this authorProf. Dr. Yingfu Li, Corresponding Author liying@mcmaster.ca Department of Biochemistry and Biomedical Sciences and Department of Chemistry and Chemical Biology, McMaster University, 1200 Main Street West, Hamilton, Ontario, L8N 3Z5 (Canada), Fax: (+1) 905-522-9033Department of Biochemistry and Biomedical Sciences and Department of Chemistry and Chemical Biology, McMaster University, 1200 Main Street West, Hamilton, Ontario, L8N 3Z5 (Canada), Fax: (+1) 905-522-9033Search for more papers by this author This work was supported by the Natural Sciences and Research Council of Canada (NSERC) and Sentinel Bioactive Paper Network. Y.L. is a Canada Research Chair. Give accessShare full text accessShare full-text accessPlease review our Terms and Conditions of Use and check box below to share full-text version of article.I have read and accept the Wiley Online Library Terms and Conditions of UseShareable LinkUse the link below to share a full-text version of this article with your friends and colleagues. Learn more.Copy URLShare a linkShare onEmailFacebookTwitterLinked InRedditWechat Lighting up bacteria: An RNA-cleaving fluorescent DNAzyme (RFD) can produce a fluorescent signal in the crude extracellular mixture generated by live bacterial cells (see picture). These DNAzymes cleave a lone RNA linkage (R) embedded in a DNA chain and flanked by nucleotides labeled with a fluorophore (F) and a quencher (Q). Detailed facts of importance to specialist readers are published as ”Supporting Information”. Such documents are peer-reviewed, but not copy-edited or typeset. They are made available as submitted by the authors. Please note: The publisher is not responsible for the content or functionality of any supporting information supplied by the authors. Any queries (other than missing content) should be directed to the corresponding author for the article. The full text of this article hosted at iucr.org is unavailable due to technical difficulties. Please check your email for instructions on resetting your password. If you do not receive an email within 10 minutes, your email address may not be registered, and you may need to create a new Wiley Online Library account. Can\'t sign in? Forgot your username? Enter your email address below and we will send you your username If the address matches an existing account you will receive an email with instructions to retrieve your username