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Aves Labs/RGS14 (7x-170)/Purified Trial-Size (75-170-020)

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PurifiedTrial-Size(75-170-020)

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4000-520-616

产品说明

Volume: Purified: 100 µL; Purified Trial: 20 µL; TC Supernatant: 5 mLConcentration: Purified: 1 mg/mL; TC Supernatant: Lot SpecificClonality: MonoclonalForm: Purified and TC Supernatant Available (select your preferred form, size and quantity before clicking "Add to Cart")Host Species: MouseImmunogen: Fusion protein amino acids 1-544 (full-length) of rat RGS14 (also known as Regulator of G-protein signaling 14, RAP1/RAP2-interacting protein and RPIP1, accession number O08773)Mouse: 95% identity (524/547 amino acids identical)Human: 86% identity (475/547 amino acids identical)45% identity with RGS12 and other RGS proteinsEpitope mapped to within amino acids 444-490 (between 2nd Ras-binding GoLoco domains, PDAKTREASSIPPCRSQGCLPRTQTKDSHLPPLSSSLSVEDASGSTG, 2014 Evans et al J Comp Neurol)Mouse: 85% identity (40/47 amino acids identical)Human: 51% identity (24/47 amino acids identical)Target Description: RGS14 is a member of the RGS family (regulator of G-protein signaling) and is highly expressed in the prefrontal cortex. Hallmark domains of RGS14 include a RGS domain, two Raf-like Ras-binding domains and a GoLoco motif. RGS14 inactivates G protein α subunits. Alterations in this protein have been implicated in Schizophrenia and Alzheimer’s disease.Gene ID: Rgs14Antibody Registry ID (RRID): AB_2179931Physical State: LiquidValidation and Application NotesMolecular Weight: 60 kDaNOTEAves Labs products are intended for use as research laboratory reagents. They are not intended for use as diagnostic or therapeutic reagents in humans.↑ back to top

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该系列产品主要用于神经元细胞的各亚细胞结构研究，可与现有的小鼠/兔抗体进行免疫双标，反应性包括人、小鼠等多个哺乳类动物。在保证抗体特异性的前提下，部分产品可分为抗不同的氨基酸片段。该系列产品包括抗APP3/APP345/APP4/APP5/ABN/TUJ/CAT/ DCX/ER1/ER2/ER3/ER5/GAD/GAP43/MAP/NET/ NUN/NSE/ NFH / NFL / NFM / PER/ PRN / PAP/ STG / TAU / TYH的抗体。除单独的抗体提供，我们还可同时提供1/3种任意抗体组合及相应二抗的试剂盒，以更优惠的价格及便捷性以满足研究人员的不同需要。