提醒:代购产品,无质量问题不接受退换货,下单前请仔细核对信息。下单后请及时联系客服 核对商品价格,订单生效后再付款。
Irvine Scientific/Recombinant Human TNF-alpha ACF/10 µg/95117-10 µg
价格:

自营商城

解放采购

正品保障

及时交付

厂家直采

一站服务

货号:
品牌:
会员服务:
尊享会员价
贵宾专线
运费优惠
闪电退款
福利优惠
上门换新
友情提示
以上价格仅为参考,请联系客服询价。
免费咨询热线
4000-520-616
产品说明
Tumornecrosisfactor-alpha(TNF-alpha)isapleiotropicinflammatorycytokineproducedpredominantlybyinflammatorymonocytesandmacrophages,butothercelltypes,includingneutrophils,endothelialcells,lymphocytes,andactivatedtissuecells,canalsobeasourceduringoverwhelminginflammatoryresponses.TNF-alphahasbothbeneficialanddestructivepropertiesforthecentralnervoussystemandaffectslipidmetabolism,coagulation,andendothelialfunction.TheincreasingreleaseofTNF-alphamaycontributetotheoddsofischemicstrokeinpatients.TNF-alphaisaprimarymediatorofnumerousimmunologicfunctions,whichincludestimulatingphagocytosisinmacrophages,chemoattractionofneutrophils,increasedinsulinresistance,andinducingfever.Asacentralplayerinthecytokinenetwork,TNF-alphahasbeenimplicatedinavarietyofdiseasestates,includingcachexia,septicshock,acuterespiratorydistresssyndrome,andanumberofnecrotic,proliferativeandautoimmunediseases.TNF-alphaactivatessignalsthroughtworeceptors,TNFR1,whichisexpressedonmostcelltypes,andTNFR2,whichisexpressedmainlyonimmunecells.TNF-alphaexistsinbothsecretedandmembraneboundforms,bothbioactive(1-5).RecombinantHumanTNF-alphaisanon-glycosylatedprotein,containing158aminoacids,withamolecularweightof17.5kDa.•AccessionNumber:P01375•Synonyms:TNFSF2,Cachectin,DIF,Necrosin,Cytotoxin,Cachexin,TNF,TNF-α•Purity:≥96%purity.Determinedbyreducingandnon-reducingSDS-PAGEanalysis.•Bioactivity:ED50isdeterminedbythecytolysisofmouseL929cellsinthepresenceofActinomycinD.TheED50istypicallylessthan0.8ng/mL.•Animalcomponent-freeandcarrier-free•CustompackagingavailableForresearchorfurthermanufacturinguseonly.Alsoavailableinothersizes.

FUJIFILM Irvine Scientific是一家全球生命科学和医学媒体提供商,提供一系列创新产品,以帮助推动客户医疗保健事业的发展。我们独特的产品和服务组合以及监管经验,使我们能够为客户不断变化的需求提供可靠的支持系统。我们真诚地倾听客户的意见,并真正关心他们的业务及其成功。

我们致力于支持生物制药行业成功开发和商业化人类疗法和疫苗的承诺体现在我们的技术,支持和供应能力的不断契合,以满足和超越了工业细胞培养市场的独特要求。FUJIFILM Irvine Scientific在保持超过45年的独特灵活性和专注性的媒体公司的同时,已稳步发展成为全球战略供应商,以支持我们的客户从早期开发到商业化。