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Creative PEGWorks /mPEG-ALD, MW 40k/1g/PLS-247-1g

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PLS-247-1g

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Catalog No. :PLS-247Product Name :mPEG-ALD,MW 40kDescription :mPEG-aldehyde (propionaldehyde) reacts with amine and N-terminal of peptide and protein to form an imine containing a C=N double bond, which can be further reduced. PEG aldehyde or ketone derivatives can be used in reversible PEGylation through its reaction with hydrazine or hydrazide forming a hydrolytic acyl hydrozone linkage. PEG butyraldehyde may be offered through custom synthesis. References: 1. The effect of the acid-sensitivity of 4-(N)-stearoyl gemcitabineloaded micelles on drug resistance caused by RRM1 overexpression, Biomaterials. 2013 March; 34(9): 2327–2339, Text. 2. Fluorinated block co-polymers. U.S. Patent No. 8,691,284. 8 Apr. 2014. Text 3. Biocompatible adhesive polymers.Biocompatible adhesive polymers. U.S. Patent No. 8,907,045. 9 Dec. 2014. Text 4.Mechanically tunable, human mesenchymal stem cell viable poly(ethylene glycol)–oxime hydrogels with invariant precursor composition, concentration, and stoichiometry, https://doi.org/10.1016/j.mtchem.2018.11.003 5.Mechanisms of activity loss for a multi-PEGylated protein by experiment and simulation, Materials Today Chemistry, 12, 2019, 121-131, doi: 10.1016/j.mtchem.2018.12.007 Click here to view an expanded list of hundreds of publications citing Creative PEGWorks products. Structure :Price :$375/1g $1,025/5g $1,600/10g Quantity:012345678910Quantity:012345678910Quantity:012345678910

Creative PEGWorks提供一系列支持和服务，包括定制合成，聚乙二醇化，纳米颗粒药物递送，合同研发。PEGWorks具有多千克批次的生产能力。我们还提供有关药物输送和配制，蛋白质修饰和纳米颗粒表面修饰及其在制药和生物技术技术和产品中的应用的咨询服务。