长期批量供应 —— 采用重组技术,可实现快速生产 首次实验即可成功 —— 经过大量验证确认了特异性 符合伦理标准 —— 产品不含动物成分 Synthetic peptide. This information is proprietary to Abcam and/or its suppliers. 常规说明 This product is FOR RESEARCH USE ONLY. For commercial use, please contact partnerships@abcam.com.The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q As 存放说明 Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles. The Abpromise guarantee Abpromise™承诺保证使用ab7837于以下的经测试应用 \"应用说明”部分 下显示的仅为推荐的起始稀释度;实际最佳的稀释度/浓度应由使用者检定。 ICC/IF image of ab7837 stained PC12 cells. The cells were 100% methanol fixed (5 min) and then incubated in 1%BSA / 10% normal goat serum / 0.3M glycine in 0.1% PBS-Tween for 1h to permeabilise the cells and block non-specific protein-protein interactions. The cells were then incubated with the antibody (ab7837, 1µg/ml) overnight at +4°C. The secondary antibody (green) was Alexa Fluor® 488 goat anti-rabbit IgG (H+L) used at a 1/1000 dilution for 1h. Alexa Fluor® 594 WGA was used to label plasma membranes (red) at a 1/200 dilution for 1h. DAPI was used to stain the cell nuclei (blue) at a concentration of 1.43µM. 发表研究结果有使用 ab7837?请让我们知道,以便我们可以引用本数据表中的参考文章。 ab7837 被引用在 10 文献中. Kourgiantaki A et al. Neural stem cell delivery via porous collagen scaffolds promotes neuronal differentiation and locomotion recovery in spinal cord injury. NPJ Regen Med 5:12 (2020).PubMed: 32566251 Zeineldin M et al. MYCN amplification and ATRX mutations are incompatible in neuroblastoma. Nat Commun 11:913 (2020).PubMed: 32060267 Gan Q et al. Effects of Amylin Against Amyloid-ß-Induced Tauopathy and Synapse Loss in Primary Neurons. J Alzheimers Dis 70:1025-1040 (2019).PubMed: 31306122 Pathak NM et al. Novel dual incretin agonist peptide with antidiabetic and neuroprotective potential. Biochem Pharmacol 155:264-274 (2018).PubMed: 30028989 Millar P et al. Metabolic and neuroprotective effects of dapagliflozin and liraglutide in diabetic mice. J Endocrinol 234:255-267 (2017).PubMed: 28611211 Sooy K et al. Cognitive and Disease-Modifying Effects of 11ß-Hydroxysteroid Dehydrogenase Type 1 Inhibition in Male Tg2576 Mice, a Model of Alzheimer\'s Disease. Endocrinology 156:4592-603 (2015). MousePubMed: 26305888 McClean PL Hölscher C Liraglutide can reverse memory impairment, synaptic loss and reduce plaque load in aged APP/PS1 mice, a model of Alzheimer\'s disease. Neuropharmacology 76 Pt A:57-67 (2014).PubMed: 23973293 Faivre E Hölscher C D-Ala2GIP facilitated synaptic plasticity and reduces plaque load in aged wild type mice and in an Alzheimer\'s disease mouse model. J Alzheimers Dis 35:267-83 (2013). MousePubMed: 23568101 Faivre E Hölscher C Neuroprotective effects of D-Ala(2)GIP on Alzheimer\'s disease biomarkers in an APP/PS1 mouse model. Alzheimers Res Ther 5:20 (2013). MousePubMed: 23601582 McClean PL et al. The diabetes drug liraglutide prevents degenerative processes in a mouse model of Alzheimer\'s disease. J Neurosci 31:6587-94 (2011). IHC-FoFr MousePubMed: 21525299 Blocking step Serum as blocking agent for 30 minute(s) Concentration: 5% Temperature: 22 C Blocking step Serum as blocking agent for 30 minute(s) Concentration: 5% Temperature: 25 C Thank you for contacting us.Here please find the information about our testing discount program. Below I also include information about our Abpromise guarantee. For UNTESTED species and/or applications, we have established a testing discount program. Here is a brief description of how it works: The testing discount program is for customers who like to use an antibody/protein on an untested species/application. You would purchase the antibody at full price, test it and submit an Abreview with your data (positive or negative). On your next order you will receive a discount for ONE antibody at the full price (100%) of the antibody you have tested. The terms and conditions applicable to this offer can be found here: https://www.abcam.com/collaborationdiscount.Abpromise guarantee: We guarantee all our products for TESTED species and applications as listed on the datasheet. The guarantee is valid for 6 months after a purchase. For more details about our Abpromise guarantee please check this link: https://www.abcam.com/abpromise. I hope this information is helpful to you. Please do not hesitate to contact us if you need any more advice or information. Read MoreThank you for your enquiry. To our knowledge, this antibody has yet to be tested in IF. All tested applications are specified on Abcam product datasheets. If you decide to go ahead and purchase this product, please let us know how you get on and in return we will forward a reward of your choice, typically an Amazon gift voucher. Read More This antibody has not yet been tested for cross reactivity with rat. However, it works well in IHC and is a polyclonal and will thus recognise a number of epitopes on the immunogen. So it is possible that it will cross react with rodent synaptophysin. Should you decide to go ahead and test this antibody, please let us know how you get on, and in return we will forward a USD15/EUR15/GBP10 Amazon gift voucher. Read More The anitbody has not yet been tested for cross reativity with rat and mouse. However, it works well in IHC and is a polyclonal and will thus recognise a number of epitopes on the immunogen. I\'d therefore predict that it will cross react with rodent synaptophysin. Read MorePlease note: All products are FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC PROCEDURES For licensing inquiries, please contact partnerships@abcam.com