首页 > Caltag > Caltag/TIM-3 Detection Set (Risk Free)/1Set/PSI-RF16100

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Caltag/TIM-3 Detection Set (Risk Free)/1Set/PSI-RF16100

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PSI-RF16100

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Caltag

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TIM-3 Detection Set (Risk Free)Product Code: PSI-RF16100 Pack Size: 1Set Form: Detection Set Applications: WB, Immunocytochemistry (ICC), Immunohistochemistry- Paraffin Embedded (IHC-P), Flow Cytometry, Immunofluorescence (IF)Shipping Temp: blue ice Storage Temp: Antibodies can be stored at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures. Target Species: HumanProduct Type: Antibody Kits Description: TIM-3 antibody was raised against the extracellular domain of human TIM-3 Optimal dilutions for each application to be determined by the researcher. Supplier: ProSci Product Category: Antibodies by Application > Monoclonal AntibodiesThe immune checkpoint protein TIM3 is a member of the immunoglobulin superfamily and TIM family of proteins that was initially identified as a specific marker of fully differentiated IFN-? producing CD4 T helper 1 (Th1) and CD8 cytotoxic cells. It is a Th1-specific cell surface protein that regulates macrophage activation and negatively regulates Th1-mediated auto- and alloimmune responses, and is also highly expressed on regulatory T cells, monocytes, macrophages, and dendritic cells (1). TIM3 and PD-1 are co-expressed on most CD4 and CD8 T cells infiltrating solid tumors or in hematologic malignancy in mice; blocking TIM3 in conjugation with a PD-1 blockade increases the functionality of exhausted T cells and synergizes with to inhibit tumor growth (2,3).ProSci"s Risk-FreeTM antibodies are mouse monoclonal antibodies made to improve in vivo studies. Unlike antibodies developed using proteins made in yeast or bacteria, Risk-FreeTM antibodies are developed with antigens expressed in mammalian cell lines, giving the most native post-translational modifications to the protein.Validated for flow cytometry and ELISA Rigorously tested for the following applications: Immunoblot Immunohistochemistry Immunocytochemistry Immunofluorescence Multiple antibodies per target allowing the user to choose the best antibody for their application Available individually or as a set Risk-FreeTM means they are guaranteed to work for their approved applicationsDownload Product DocumentationProduct InformationProduct Code: PSI-RF16100 Price (1Set): £409.00 excluding VATQuantity: Add to basketDo you require further information?Enquire OnlineContact UsRequest a call-back

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我们的流式细胞仪产品范围包括用于免疫表型分析的Euroflow IVD验证试剂，以及用于检测血液系统恶性肿瘤，最小残留疾病和原发性免疫缺陷的筛查管，以及同型对照和校准颗粒。

与我们的IVD抗体面板同时提供TransFix；一种IVD细胞抗原稳定溶液，可防止多种标本类型的细胞降解，以进行流式细胞术分析。稳定的标本类型包括全血，脑脊液，骨髓，循环肿瘤细胞和动物血液。另外，我们提供FlowStainer；用于抗体存储，鸡尾酒混合，细胞洗涤，红细胞裂解和离心的自动免提样品制备仪器，用于复杂的流式细胞仪。