About usIProductsITechnology Package InsertsIMSDSul {list-style-type: none;padding-left: 10px;/*margin-left: 10px;*/} Home > Products > Haemostasis Kits > APCR-Vul {list-style-type: none;padding-left: 10px;/*margin-left: 10px;*/}/*icons*/.jsmenu-icon{width: 15px;height: 15px;float: left;background: url("/il/images/jsmenu/32px.png");position:relative;background-repeat: none;}.jsmenu-icon.jsmenu-withchildren{background-position: -110px -8px;}.jsmenu-icon.jsmenu-main-open{background-position: -38px -8px;}.jsmenu-icon.jsmenu-open{background-position: -141px -8px;}.jsmenu-icon.jsmenu-current{/*background-position: -72px -72px;*/}.jsmenu-icon.jsmenu-leaf{background-position: -78px -8px;}a.jsmenu-main-open,a.jsmenu-open,a.jsmenu-withchildren,a.jsmenu-leaf{color: white;}a:hover.jsmenu-main-open,a:hover.jsmenu-open,a:hover.jsmenu-withchildren,a:hover.jsmenu-leaf{color: orange;}a.jsmenu-current{color: orange;}#jsMenu li {font-size: 12px;clear:both;}ProductsHaemostasis KitsAPC-RAPCR-VCOATEST®...COATEST®...Protein C - Protein SFactor VIIFactor VIIIHeparinCalibrators & ControlsBio-ReagentsChromogenic SubstratesAPC Resistance determination due to Factor V Leiden mutationHigh discrimination between genotypes with 100% sensitivity for FV:Q506. Reduces need for PCR determination. Applicable to anticoagulant treated patients.COATEST® APCTM RESISTANCE VAn APTT-based kit for screening of factor V-related APC resistance. The high sensitivity and specificity of the test for the factor V:Q506 mutation is obtained by prediluting the sample plasma with an excess of V-DEF Plasma. The test design makes it possible to discriminate between heterozygous and homozygous factor V genotypes. It also allows for analysis of plasma from patients on heparin or oral anticoagulant therapy.Measurement PrincipleOne volume of plasma is prediluted with four volumes of V-DEF Plasma. The dilution is then incubated with the APTT reagent for a standard period of time. Coagulation is triggered by the addition of CaCl2 in the absence and presence of exogenous APC and the time for clot formation is recorded.Reagents and their stability when openedAPC/CaCl24x2 ml5 days2-8°C8 hours15-25°CAPTT reagent1x16 ml1 week15-25°C1 month2-8°CCaCl21x8 ml1 month2-8°C1 week15-25°CV-DEF Plasma4x4 ml8 hours15-25°C24 hours2-8°C3 months-20°CAPC/CaCl24x2 ml3 months-20°CControl Plasma Level 11x1 ml6 hours2-25°C3 months-20°CControl Plasma Level 21x1 ml6 hours2-25°C3 months-20°CDeterminations80-160Part Number: 82 3120 63COATEST® APCTM RESISTANCE V-SAn APTT-based kit for screening of factor V-related APC resistance. The high sensitivity and specificity of the test for the factor V:Q506 mutation is obtained by prediluting the sample plasma with an excess of V-DEF Plasma. The test design makes it possible to discriminate between heterozygous and homozygous factor V genotypes. It also allows for analysis of plasma from patients on heparin or oral anticoagulant therapy.Measurement PrincipleOne volume of plasma is prediluted with four volumes of V-DEF Plasma. The dilution is then incubated with the APTT reagent for a standard period of time. Coagulation is triggered by the addition of CaCl2 in the absence and presence of exogenous APC and the time for clot formation is recorded.Reagents and their stability when openedV-DEF Plasma2x4 ml8 hours15-25°C24 hours2-8°C3 months-20°CCaCl22x2 ml1 week15-25°C1 month2-8°CAPTT reagent2x4 ml1 week15-25°C1 month2-8°CAPC/CaCl22x2 ml8 hours15-25°C5 days2-8°C3 months-20°CControl Plasma Level 11x1 ml6 hours2-25°C3 months-20°CControl Plasma Level 21x1 ml6 hours2-25°C3 months-20°CDeterminations40-80Part Number: 82 3138 63© Copyright 2021. All rights reserved. Chromogenix is a brand of Instrumentation Laboratory Home  I  Site Map