Anti-CD278 In Vivo Antibody – Low Endotoxin (7E.17G9) [ICH1082]$320.00 – $2,378.00Size:Choose an option5mg25mg50mg100mgEndotoxin Level:Choose an optionLowUltra lowClearAnti-CD278 In Vivo Antibody – Low Endotoxin (7E.17G9) [ICH1082]Anti-CD278 In Vivo Antibody - Low Endotoxin (7E.17G9) [ICH1082] quantity— OR —Add to cartSKU: ICH1082Categories: anti-mouse, Blocking, Flow Cytometry, Functional Assays, Low Endotoxin, Ultra Low Endotoxin, Western BlotBrowseAntibodiesBiosimilar AntibodiesIsotype ControlsLow EndotoxinUltra Low EndotoxinAntibody Labeling KitsApplicationsBlockingCODEXCyTOFDot BlotELISAELISpotFlow CytometryFlow Cytometry (intracellular)Functional AssaysIHC (Frozen)IHC (Paraffin)ImmunoCytoChemistryImmunofluorescenceImmunoprecipitationIn Situ HybridizationIn Vivo DepletionIP-Mass SpectrometryNeutralizationWestern BlotConjugatedAPCBiotinDyLight 488DyLight 550DyLight 594DyLight 633DyLight 650DyLight 680DyLight 755DyLight 800FITCPEPE/Cy7PerCPDetergentsFc-SilencedGel StainInhibitorsRecombinant ProteinsSpecies Reactivityanti-bovineanti-chickenanti-humananti-mouseanti-ratMonkeyDescriptionAdditional informationReviews (0)Bulk anti-CD278 In Vivo Antibody – Low Endotoxin (7E.17G9)Product Benefits:ichorbio’s anti-CD278 In Vivo Antibody – Low Endotoxin (7E.17G9) is manufactured in a cGMP compliant, ISO Quality Standard 9001:2015 facility. ichorbio’s low endotoxin antibodies have half the endotoxin of comparable antibodies from our competitors at less than 1.0 EU/mg. If ichorbio’s low endotoxin antibodies are not low enough we also offer ultra low endotoxin antibodies which have even less endotoxin (<0.75EU/mg) at an even higher purity (98% versus 95%). ichorbio offers Amazon vouchers or donations to the NC3Rs for reviews of this product: click here for more information. ichorbio: the best antibodies for in vivo research.Target:CD278Clone:7E.17G9Isotype:Rat IgG2bOther Names:Inducible T-cell costimulator, Icos, Activation-inducible lymphocyte immunomediatory molecule, CD28 and CTLA-4-like protein, CCLP, CD28-related protein 1, CRP-1, AilimUniprot:Q9WVS0Host:RatSpecies Reactivity:MouseSpecificity:Anti-CD278 In Vivo Antibody – Low Endotoxin (7E.17G9) recognizes an epitope on Mouse ICOSPurification Method:This monoclonal antibody was purified using multi-step affinity chromatography methods such as Protein A or G depending on the species and isotype.Background:Inducible co-stimulator (ICOS), also called ALIM and H4, is a homodimeric protein and member of the CD28 family of immune co-stimulatory receptors. Other family members are CD28, CTLA-4 and PD-1. ICOS enhances all basic T cell responses to a foreign antigen, namely proliferation, secretion of lymphokines, up-regulation of molecules that mediate cell-cell interaction, and effective help for antibody secretion by B cells. Unlike the constitutively expressed CD28, ICOS has to be de novo induced on the T cell surface, does not up-regulate the production of IL-2, but superinduces the synthesis of IL-10, a B cell-differentiation factor. In vivo, ICOS is highly expressed on tonsillar T cells, which are closely associated with B cells in the apical light zone of germinal centres, the site of terminal B cell maturation. ICOS regulates CD28-dependent and CD28-independent CD4 (+) subset (Th1 and Th2) responses. It is a major regulator of the adaptive immune system and therefore, has a protective role in inflammatory autoimmune diseases.Concentration:1.0 – 5.0 mg/mlFormulation:0.01 M phosphate buffered saline (PBS) pH 7.2, 150 mM NaCl with no carrier protein, potassium or preservatives added. BSA and Azide free.Purity:>95% by SDS-PAGE and HPLC>98% by SDS-PAGE and HPLCEndotoxin:≤ 1.0 EU/mg as determined by the LAL method≤ 0.75 EU/mg as determined by the LAL methodAggregation:Aggregation level ≤ 5%Aggregation level ≤ 1%IMPACT Pathogen Test:We use the IMPACT test generated by IDEXX Laboratories to guarantee our Ultra Low Endotoxin antibodies are pathogen free. Our rat antibodies are tested for:Mycoplasma sppMycoplasma pulmonisPneumonia virus of miceKilham’s rat virusToolan’s H1 virusRat parvovirusLymphocytic choriomeningitis virusRat cytomegalovirusSendai virusRat coronavirusSialodacryoadenitis virusRat minute virusSeoul virusMouse adenovirusReovirus 3Rat theilovirusStorage:anti-CD278 In Vivo Antibody – Low Endotoxin (7E.17G9) is stable when stored at 2-8°C. Do not freeze. For long term storage aseptically aliquot in working volumes without diluting and store at –80°C. Avoid Repeated Freeze Thaw Cycles.Applications:Western Blot, Blocking, Functional Assays, Flow CytometryApplication Notes:Each investigator should determine their own optimal working dilution for specific applications.Use:Products are for research use only. Not for use in diagnostic or therapeutic procedures.Isotype Control:Rat IgG2b In Vivo Isotype Control – Low Endotoxin [1-2] (ICH2243)Related Antibody:Anti-CD278 In Vivo Antibody – Ultra Low Endotoxin [7E.17G9] (ICH1082UL)Size:1mg, 5mg, 25mg, 50mg, 100mgEndotoxin Level:Low, Ultra lowReviewsThere are no reviews yet.Be the first to review “Anti-CD278 In Vivo Antibody – Low Endotoxin (7E.17G9) [ICH1082]” Cancel replyYour rating*Rate…PerfectGoodAverageNot that badVery poorYour review*Name*Email* Save my name, email, and website in this browser for the next time I comment. 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