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Immuno Star/Gastrin Releasing Peptide (GRP) / Bombesin Antibody/20073
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产品说明
The ImmunoStar Gastrin Releasing Peptide antiserum was quality control tested using standard immunohistochemical methods. The antiserum demonstrates strongly positive labeling of rat dorsal horn of spinal cord using indirect immunofluorescent and biotin/avidin-HRP techniques. Recommended primary dilution is 1/1,000-1/2,000 in PBS/0.3% Triton X-100 - Bn/Av-HRP Technique. Staining is completely eliminated by pretreatment of 1 mL of diluted antibody with 50 µg of bombesin.Photo Description: IHC of at stomach staining for gastrin releasing peptide. The tissue was fixed with 4% formaldehyde in phosphate buffer, before being removed and prepared for frozen sectioning. Sections were incubated at RT in 10% goat serum in PBS, before standard IHC procedure. Primary antibody was incubated at 1:2000 for 48 hours, goat anti-rabbit secondary was subsequently added for 1 hour after washing with PBS. Light microscopy staining was achieved with standard biotin-streptavidin/HRP procedure and DAB chromogen and counterstained with hematoxylinHost: RabbitQuantity / Volume: 100 µLState: Lyophilized Whole SerumReacts With: Chick, Hamster, Human, Mouse, Newt, Pigeon, Quail, Rabbit, Ram (Sheep), Rat, Zacco Platypus (Minnow)Availability: In StockPreabsorption Control: Available at irbiologicals, Catalog # IRCP069. Sequence: Glp-Gln-Arg-Leu-Gly-Asn-Gln-Trp-Ala-Val-Gly-His-Leu-Met-NHAlternate Names: BN; GRP-10; proGRP; preproGRP; gastrin-releasing peptide, anti-GRP, Bombesin, anti-BombesinGene Symbo: GRPRRID: AB_572221Database Links: Entrez Gene: 425213 Chick Entrez Gene: 100769410 Hamster Entrez Gene: 2922 Human Entrez Gene: 225642 Mouse Entrez Gene: 102093899 Pigeon Entrez Gene: 107325907 Quail Entrez Gene: 103349406 Rabbit Entrez Gene: 443332 Ram (Sheep) Entrez Gene: 171101 Rat
ImmunoStar的5-HT(血清素)抗体是由麦迪逊威斯康星大学兽医学院比较生物科学系副教授Mark Brownfield博士设计的。他的高度重视的血清素抗体研究小组是ImmunoStar独有的,并因其有效的血清素抗体而在研究人员中赢得了声誉。
布朗菲尔德博士在血清素能系统及其对脑功能的影响方面的工作集中在血清素能神经元及其靶神经元的分子解剖学上。他针对血清素能系统的抗体包括血清素前体(5-羟色氨酸)的抗血清,初级代谢产物(5-羟吲哚乙酸),血清素转运蛋白(一类抗抑郁药的靶标)的抗体和五个血清素受体(5HT1a, 5HT2a,5HT2c,5HT5a和5HT7)。
Brownfield博士的5HT(5-羟色胺)研究表明,血清素能系统与神经内分泌,自主神经,情绪,昼夜节律,视觉和运动系统中重要的回路之间存在相关性。
出版物 –通过抗体名称,编号,作者,物种和其他关键字在我们的出版物数据库中搜索5-HT血清素的研究。
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