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Innoprot/Human Tracheal Smooth Muscle Cells/P10562

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P10562

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Product Description Specifications Characterization Similars Publications Technical Resources & ProtocolsAirway smooth muscle is fundamental for maintaining airway tone. The specialized ultrastructural features and regulatory mechanisms of airway smooth muscle are vital for normal airway function. Previous studies have shown that airway smooth muscle undergoes phenotypic changes during development and in various respiratory disorders. Airway smooth muscle may also mediate the immune response by secreting cytokines and chemokines. Cultured tracheal smooth muscle cells (TSMC) express three p21-activated kinase (PAK) isoforms which may promote TSMC migration by signaling to p38 MAPK. Human Tracheal Smooth Muscle Cells proliferation is an important component of airway remodeling in asthma. It is consequently a target for the development of novel anti-asthma agents.Reference: P10562Size/Quantity: 5x105 cells / vialProduct Use: For research use onlyShipping Conditions: Dry IceData Sheet - Cell Cuture Manual

Innoprot是一家生物技术公司，成立于2007年，是巴斯克地区大学的附属公司。Innoprot提供产品和技术，用于在药物发现和开发中对基于细胞的测定进行多路复用，包括原代细胞，永生细胞系和重组细胞系。凭借专有的GPCR筛选技术，Innoprot能够鉴定具有最高效力的化合物，同时避免了不良副作用。

Innoprot还担任CRO，提供针对GPCR，纤维化和神经退行性疾病（例如阿尔茨海默氏病，帕金森氏病或ALS）的筛查服务。

Inno prot的私人员工将药物发现技术领域的经验与制药服务提供商广泛的职业道路相结合。