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Tocris/N-Acetylpuromycin/5679/10/10 mg
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Description:DownregulatesSnoNandSkiproteinexpression;promotesTGF-βsignaling
ChemicalName:3'-[[(2S)-2-(Acetylamino)-3-(4-methoxyphenyl)-1-oxopropyl]amino]-3'-deoxy-N,N-dimethyladenosine
Purity:≥98%(HPLC)
BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences
BiologicalActivity
DownregulatesSnoNandSkiproteinexpression;promotesTGF-βsignaling,independentlyofMAPKactivation.Doesnotbindribosomesorblockproteinsynthesis.
TechnicalData
M.Wt | 513.55 |
Formula | C24H31N7O6 |
Storage | Storeat-20°C |
Purity | ≥98%(HPLC) |
CASNumber | 22852-13-7 |
PubChemID | 46173769 |
InChIKey | LADKVYSQIGJMFP-IYRMOJGWSA-N |
Smiles | O[C@@H]1[C@H](NC([C@@H](NC(C)=O)CC4=CC=C(OC)C=C4)=O)[C@@H](CO)O[C@H]1N3C2=NC=NC(N(C)C)=C2N=C3 |
Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.
AllTocrisproductsareintendedforlaboratoryresearchuseonly.
SolubilityData
Solvent | MaxConc.mg/mL | MaxConc.mM | |
---|---|---|---|
Solubility | |||
1eq.HCl | 51.35 | 100 | |
DMSO | 51.35 | 100 |
PreparingStockSolutions
Thefollowingdataisbasedontheproductmolecularweight513.55.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.
Concentration/SolventVolume/Mass | 1mg | 5mg | 10mg |
---|---|---|---|
1mM | 1.95mL | 9.74mL | 19.47mL |
5mM | 0.39mL | 1.95mL | 3.89mL |
10mM | 0.19mL | 0.97mL | 1.95mL |
50mM | 0.04mL | 0.19mL | 0.39mL |
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ReconstitutionCalculator
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DilutionCalculator
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ProductDatasheets
CertificateofAnalysis/ProductDatasheet
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