BiologicalActivity
Sesquiterpenelactone.Inducesactivin/SMAD3signalinganddisruptsCripto-1/activinreceptortypeIIAinteraction.DisplaysantiproliferativeactivityinhumancolonadenocarcinomaHCT-8cells.
CompoundLibraries
AlantolactoneisalsoofferedaspartoftheTocriscreenPlus.FindoutmoreaboutcompoundlibrariesavailablefromTocris.
TechnicalData
| M.Wt | 232.32 |
| Formula | C15H20O2 |
| Storage | Storeat-20°C |
| Purity | ≥98%(HPLC) |
| CASNumber | 546-43-0 |
| PubChemID | 72724 |
| InChIKey | PXOYOCNNSUAQNS-AGNJHWRGSA-N |
| Smiles | O=C3C([C@@]2([H])C=C1[C@@H](C)CCC[C@@](C)1C[C@]([H])2O3)=C |
Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.
AllTocrisproductsareintendedforlaboratoryresearchuseonly.
SolubilityData
| Solvent | MaxConc.mg/mL | MaxConc.mM | |
|---|---|---|---|
| Solubility | |||
| DMSO | 23.23 | 100 | |
| ethanol | 23.23 | 100 |
PreparingStockSolutions
Thefollowingdataisbasedontheproductmolecularweight232.32.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.
| Concentration/SolventVolume/Mass | 1mg | 5mg | 10mg |
|---|---|---|---|
| 1mM | 4.3mL | 21.52mL | 43.04mL |
| 5mM | 0.86mL | 4.3mL | 8.61mL |
| 10mM | 0.43mL | 2.15mL | 4.3mL |
| 50mM | 0.09mL | 0.43mL | 0.86mL |
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