- Hemoglobin voids in flow-through >95%, with<30 minute bind/wash microfuge protocol
- Low abundance enrichment and proteolytic trypsindigestion on the same bead.
- Consumable, cost-effective, no columnregeneration or cross-contamination
- Species agnostic; human, rat, mouse, goat, sheep,porcine and bovine sera have been tested
- Trypsin digestion on the bead
- Seamless workflows and unique proteolyticefficiencies
- No in-gel digests, no solution digests, no C18 desalting, more consistent, reproducible results
- Compatibility with quantitative label (i.e., iTRAQ) and label-free LC-MS methods
HemoVoid™ LC-MS On-Bead is an hemoglobin depletion and enzymatic proteolytic digestion reagent kit. It removes hemoglobin from serum and plasma samples while concentrating low abundance proteins on the beads. It is ideal for applications involving LC-MS discovery and targeted proteomics.
The HemoVoid™ beads are derived from a silica-based library of individual mixed-mode polymeric ligands. The library was designed to facilitate weak binding of proteins, allowing for progressive enrichment of the low abundance proteome, with specialized voiding properties empirically derived. The HemoVoid™ beads have been adapted to a protocol specifically designed for LC-MS applications whereby the low abundance proteome adsorbed to the bead is proteolytically degraded to its peptide constituents. In this way HemoVoid™ LC-MS On-Bead integrates low abundance enrichment, with Trypsin (or other suitable protease) on-bead digestion, in a simple, highly efficient and seamless workflow for LC-MS discovery and quantitative analyses.
Click here for the HemoVoid™ LC-MS On-Bead For RBC Proteomics Product Sheet美国BSG(BiotechSupportGroup""LLC)公司是一家公司是一家全球知名的蛋白质组和基因组样本预处理的公司,是这个领域公认的领导者,该公司将其发明的专利表面化学技术应用生物学领域,比其他方法如亲合技术,苯酚法有绝对的优势。由于技术上的领先,使得BSG公司的产品广泛被美国国家基因组研究所,斯坦福大学等重要机构使用。
美国BSG(Biotech Support Group,LLC)公司是一家公司是一家全球知名的蛋白质组和基因组样本预处理的公司,是这个领域公认的*,该公司将其发明的表面化学技术应用生物学领域,比其他方法如亲合技术,苯酚法有绝对的优势。由于技术上的,使得BSG公司的产品广泛被美国国家基因组研究所,斯坦福大学等重要机构使用。(http://www.biotechsupportgroup。。com/) 目前我司成功取得美国BSG中国总代理,BSG各大产品均可在我司查询订购。 分子生物学 Ambion,Biosearch Technologies,Biotium,BPS bioscience,Dharmacon,Glen Research,HYQ ,Lucigen, lumiprobe,MO BIO,Molecular probes,NEB,Qiagen 细胞生物学 AddEXBIO,Cellgro,Echelon,Equitech,Gemini,Gibco,InvivoGen,Mlltenyi,Partec,Spherotech,Stemcell Abbiotec,Abcam,ABD SEROtec,Abnova,ADI,Antibodies-Online,AssayPro,Biorbyt,BioVision,BTI,Cellgro,CST,chromotek,Covance,Echelon,Endocrine Tech,Epitomics ,FD Neuro Technologies,Fitzgerald,GeneTex,GenWay,Gibco,Invitrogen,Invivogen,Jackson,Lifespan,LKT Labs,Miltenyi,Novex,Novus,Phoenix peptide,Pierece,,Plantmedia,Prospec,R&D,Spherotech,Stemcell,Trevigen,Santa cruz,,Separopore,USBIo,Vector Beckman coulter,BD,Biolegend,Affymetrix eBioscience,Tonbo A.G.Scientific,American Peptide,Apollo scientific,Cargille Lbs,Cayman,Nanocs,polysciences,Sigma,Tocris 诊断 Biocare,Biospacific,DIARECT,Fujirebio Diagnostics,Roche,Kamiya Epicentre,Ion Torrent,KAPA Biosystems 仪器/耗材 Applied Biosystems,Agilent,BD,Beckman coulter,Bio-Rad,GE,Perkin Elmer,Millipore,Parafilm,Uniequip
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