Tocris试剂采购 Tocris小分子,Tocris/α-Amanitin/4025/1/1 mg,DNA聚合酶,Tocris,Bio-Techne,,1 mg蚂蚁淘商城

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Tocris/α-Amanitin/4025/1/1 mg

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Tocris Bioscience

货号 /

4025/1

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4000-520-616

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Description:InhibitorofRNApolymeraseII

ChemicalName:cyclo[L-Asparaginyl-4-hydroxy-L-proly-(R-4,5-dihydroxy-L-isoleucyl-6-hydroxy-2-mercapto-L-tryptophylglycyl-L-isoleucylglycyl-L-cysteinyl]cyclic(4→8)-sulfide(R)-S-oxide

Purity:≥95%(HPLC)

BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences

BiologicalActivity

InhibitorofRNApolymeraseII.Inhibitstranscriptionineukaryoticcells.BindsandblocksthelargestsubunitsofRNApolymeraseII,preventingnewribonucleotidesfromincorporatingintothenascentRNAchain.Potentamatoxin.

TechnicalData

M.Wt	918.97
Formula	C₃₉H₅₄N₁₀O₁₄S
Storage	Storeat-20°C
Purity	≥95%(HPLC)
CASNumber	23109-05-9
PubChemID	441541
InChIKey	CIORWBWIBBPXCG-JAXJKTSHSA-N
Smiles	O=[C@@](N[C@@](C(N[C@@H](CC2=C(S4=O)NC3=C2C=CC(O)=C3)C(NCC(N[C@]([H])5[C@@H](C)CC)=O)=O)=O)([H])[C@@H](C)[C@@H](O)CO)[C@@H]1C[C@@H](O)CN1C([C@H](CC(N)=O)NC([C@H](C4)NC(CNC5=O)=O)=O)=O

Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.

AllTocrisproductsareintendedforlaboratoryresearchuseonly.

SolubilityData

	Solvent	MaxConc.mg/mL	MaxConc.mM
Solubility
	ethanol	4.59	5
	water	4.59	5

PreparingStockSolutions

Thefollowingdataisbasedontheproductmolecularweight918.97.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.

Concentration/SolventVolume/Mass	1mg	5mg	10mg
1mM	1.09mL	5.44mL	10.88mL
5mM	0.22mL	1.09mL	2.18mL
10mM	0.11mL	0.54mL	1.09mL
50mM	0.02mL	0.11mL	0.22mL

ProductDatasheets

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BiologicalActivity

TechnicalData

SolubilityData

PreparingStockSolutions

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