Tocris公司代理生物计划 Tocris Bioscience美元价/进货价,Tocris/Apcin/5747/10/10 mg,连接酶,核酸酶类,分子类,,Tocris Bioscience蚂蚁淘商城

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Tocris/Apcin/5747/10/10 mg

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Tocris Bioscience

货号 /

5747/10

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4000-520-616

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Description:Cdc20inhibitor;inhibitsCdc20-substrateinteraction

ChemicalName:3-(2-Methyl-5-nitroimidazol-1-yl)-N-(2,2,2-trichloro-1-phenylaminoethyl)propionamide

Purity:≥98%(HPLC)

BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences

BiologicalActivity

Cdc20inhibitor;inhibitsCdc20-substrateinteraction.Blockssubstrate-mediatedCdc20loADIngontotheanaphase-promotingcomplex(APC).InhibitsAPC-dependentubiquitylation.ProlongsmitoticdurationinRPE1cellsincombinationwithproTAME(prodrugofTAME(Cat.No.4506))invitro.

TechnicalData

M.Wt	438.65
Formula	C₁₃H₁₄Cl₃N₇O₄
Storage	Storeat-20°C
Purity	≥98%(HPLC)
CASNumber	300815-04-7
PubChemID	2830389
InChIKey	ZEXHXVOGJFGTRX-UHFFFAOYSA-N
Smiles	CC1=NC=C([N+]([O-])=O)N1CCOC(NC(C(Cl)(Cl)Cl)NC2=NC=CC=N2)=O

Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.

AllTocrisproductsareintendedforlaboratoryresearchuseonly.

SolubilityData

	Solvent	MaxConc.mg/mL	MaxConc.mM
Solubility
	DMSO	43.87	100
	ethanol	2.19	5mMwithgentlewarming

PreparingStockSolutions

Thefollowingdataisbasedontheproductmolecularweight438.65.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.

Concentration/SolventVolume/Mass	1mg	5mg	10mg
1mM	2.28mL	11.4mL	22.8mL
5mM	0.46mL	2.28mL	4.56mL
10mM	0.23mL	1.14mL	2.28mL
50mM	0.05mL	0.23mL	0.46mL

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