BiologicalActivity
InhibitorofSUMOylation(IC50=3μM).DirectlybindsE1andinhibitsformationofE1-SUMOintermediate.Protectsagainstamyloidβ-inducedimpairmentofneurotransmissionandsynapticplasticity.AlsosuppressesCD44andMMP14expressioninbreastcancercells,eliminatingcancerstemcellsandinhibitingtumOrigenesis.
TechnicalData
| M.Wt | 346.5 |
| Formula | C22H34O3 |
| Storage | Storeat-20°C |
| Purity | ≥97%(HPLC) |
| CASNumber | 22910-60-7 |
| PubChemID | 5281858 |
| InChIKey | YXHVCZZLWZYHSA-FPLPWBNLSA-N |
| Smiles | CCCCCC/C=CCCCCCCCC1=C(C(O)=CC=C1)C(O)=O |
Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.
AllTocrisproductsareintendedforlaboratoryresearchuseonly.
SolubilityData
| Solvent | MaxConc.mg/mL | MaxConc.mM | |
|---|---|---|---|
| Solubility | |||
| DMSO | 34.65 | 100 | |
| ethanol | 34.65 | 100 |
PreparingStockSolutions
Thefollowingdataisbasedontheproductmolecularweight346.5.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.
| Concentration/SolventVolume/Mass | 1mg | 5mg | 10mg |
|---|---|---|---|
| 1mM | 2.89mL | 14.43mL | 28.86mL |
| 5mM | 0.58mL | 2.89mL | 5.77mL |
| 10mM | 0.29mL | 1.44mL | 2.89mL |
| 50mM | 0.06mL | 0.29mL | 0.58mL |
MolarityCalculator
ReconstitutionCalculator
DilutionCalculator
ProductDatasheets
暂无品牌问答
© 2005- 苏州蚂蚁淘生物科技有限公司 版权所有。
苏ICP备17049038号-11
苏公网安备 32059002001627号
声明：本网站部分产品受外界条件影响（包含但不限于进口国出口国政策限制等因素），无法提供销售服务，下单后，会由客服人员联系厂家确认后另行通知。部分危险品无法清关，请勿下单
我要提问
您的问题将推送给已购用户，TA们将会为你解答。