BiologicalActivity
Prolyl4-hydroxylase(P4H)inhibitor;inhibitshypoxia-inducIBLefactorα(HIF-α)prolylhydroxylase(HIF-PH).IncreaseslevelsofHIF-1α;promotescellsurvivalunderhypoxicconditions.
TechnicalData
| M.Wt | 175.14 |
| Formula | C6H9NO5 |
| Storage | Storeat-20°C |
| CASNumber | 89464-63-1 |
| PubChemID | 560326 |
| InChIKey | BNJOZDZCRHCODO-UHFFFAOYSA-N |
| Smiles | O=C(C(OC)=O)NCC(OC)=O |
Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.
AllTocrisproductsareintendedforlaboratoryresearchuseonly.
SolubilityData
| Solvent | MaxConc.mg/mL | MaxConc.mM | |
|---|---|---|---|
| Solubility | |||
| DMSO | 17.51 | 100 | |
| ethanol | 17.51 | 100 | |
| water | 17.51 | 100 |
PreparingStockSolutions
Thefollowingdataisbasedontheproductmolecularweight175.14.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.
| Concentration/SolventVolume/Mass | 1mg | 5mg | 10mg |
|---|---|---|---|
| 1mM | 5.71mL | 28.55mL | 57.1mL |
| 5mM | 1.14mL | 5.71mL | 11.42mL |
| 10mM | 0.57mL | 2.85mL | 5.71mL |
| 50mM | 0.11mL | 0.57mL | 1.14mL |
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