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Tocris/(R)-2-Hydroxyglutaric acid disodium salt/6124/50/50 mg
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4000-520-616
Description:KDM4Ainhibitor;alsoNF-κBactivator
AlternativeNames:D-α-hydroxyglutaricaciddisodiumsalt
ChemicalName:(R)-2-Hydroxypentanedioicaciddisodiumsalt
BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences
BiologicalActivity
Oncometaboliteproducedbymutantisocitratedehydrogenase1(IDH1)andIDH2.InhibitsKDM4AinmurineembryonicfibroblastsresultinginactivationofmTOR.AlsoactivatesNF-κBinbonemarrowstromalcells.
TechnicalData
M.Wt | 192.08 |
Formula | C5H6Na2O5 |
Storage | Storeat-20°C |
CASNumber | 103404-90-6 |
PubChemID | 45489701 |
InChIKey | DZHFTEDSQFPDPP-HWYNEVGZSA-L |
Smiles | O[C@@H](C(O[Na])=O)CCC(O[Na])=O |
Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.
AllTocrisproductsareintendedforlaboratoryresearchuseonly.
SolubilityData
Solvent | MaxConc.mg/mL | MaxConc.mM | |
---|---|---|---|
Solubility | |||
water | 19.21 | 100 |
PreparingStockSolutions
Thefollowingdataisbasedontheproductmolecularweight192.08.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.
Concentration/SolventVolume/Mass | 1mg | 5mg | 10mg |
---|---|---|---|
1mM | 5.21mL | 26.03mL | 52.06mL |
5mM | 1.04mL | 5.21mL | 10.41mL |
10mM | 0.52mL | 2.6mL | 5.21mL |
50mM | 0.1mL | 0.52mL | 1.04mL |
MolarityCalculator
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Calculatethemass,volume,orconcentrationrequiredforasolution.
ReconstitutionCalculator
ReconstitutionCalculator
DilutionCalculator
DilutionCalculator
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ProductDatasheets
CertificateofAnalysis/ProductDatasheet
SafetyDatasheet
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