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Tocris/NKY 80/5071/50/50 mg
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4000-520-616
Description:Adenylylcyclaseinhibitor
ChemicalName:2-Amino-7-(2-furanyl)-7,8-dihydro-5(6H)-quinazolinone
Purity:≥98%(HPLC)
BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences
BiologicalActivity
Inhibitorofadenylylcyclase(AC).ExhibitsgreateraffinityforAC5overAC3andAC2(IC50valuesare8.3μM,132μMand1.7mMrespectively).
CompoundLibraries
NKY80isalsoofferedaspartoftheTocriscreenPlus.FindoutmoreaboutcompoundlibrariesavailablefromTocris.
TechnicalData
M.Wt | 229.23 |
Formula | C12H11N3O2 |
Storage | Storeat+4°C |
Purity | ≥98%(HPLC) |
CASNumber | 299442-43-6 |
PubChemID | 2772368 |
InChIKey | SOJUSNIBPPMLCC-UHFFFAOYSA-N |
Smiles | NC(N=C2)=NC1=C2C(CC(C3=CC=CO3)C1)=O |
Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.
AllTocrisproductsareintendedforlaboratoryresearchuseonly.
SolubilityData
Solvent | MaxConc.mg/mL | MaxConc.mM | |
---|---|---|---|
Solubility | |||
DMSO | 22.92 | 100 | |
ethanol | 2.29 | 10mMwithgentlewarming |
PreparingStockSolutions
Thefollowingdataisbasedontheproductmolecularweight229.23.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.
Concentration/SolventVolume/Mass | 1mg | 5mg | 10mg |
---|---|---|---|
1mM | 4.36mL | 21.81mL | 43.62mL |
5mM | 0.87mL | 4.36mL | 8.72mL |
10mM | 0.44mL | 2.18mL | 4.36mL |
50mM | 0.09mL | 0.44mL | 0.87mL |
MolarityCalculator
MolarityCalculator
Calculatethemass,volume,orconcentrationrequiredforasolution.
ReconstitutionCalculator
ReconstitutionCalculator
DilutionCalculator
DilutionCalculator
Calculatethedilutionrequiredtoprepareastocksolution.
ProductDatasheets
CertificateofAnalysis/ProductDatasheet
SafetyDatasheet
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