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Tocris/NKY 80/5071/50/50 mg
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Tocris/NKY 80/5071/50/50 mg
品牌 / 
Tocris Bioscience
货号 / 
5071/50
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4000-520-616
Description:Adenylylcyclaseinhibitor
ChemicalName:2-Amino-7-(2-furanyl)-7,8-dihydro-5(6H)-quinazolinone
Purity:≥98%(HPLC)
BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences

BiologicalActivity

Inhibitorofadenylylcyclase(AC).ExhibitsgreateraffinityforAC5overAC3andAC2(IC50valuesare8.3μM,132μMand1.7mMrespectively).

CompoundLibraries

NKY80isalsoofferedaspartoftheTocriscreenPlus.FindoutmoreaboutcompoundlibrariesavailablefromTocris.

TechnicalData

M.Wt229.23
FormulaC12H11N3O2
StorageStoreat+4°C
Purity≥98%(HPLC)
CASNumber299442-43-6
PubChemID2772368
InChIKeySOJUSNIBPPMLCC-UHFFFAOYSA-N
SmilesNC(N=C2)=NC1=C2C(CC(C3=CC=CO3)C1)=O

Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.

AllTocrisproductsareintendedforlaboratoryresearchuseonly.

SolubilityData

SolventMaxConc.mg/mLMaxConc.mM
Solubility
DMSO22.92100
ethanol2.2910mMwithgentlewarming

PreparingStockSolutions

Thefollowingdataisbasedontheproductmolecularweight229.23.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.

Concentration/SolventVolume/Mass1mg5mg10mg
1mM4.36mL21.81mL43.62mL
5mM0.87mL4.36mL8.72mL
10mM0.44mL2.18mL4.36mL
50mM0.09mL0.44mL0.87mL

ProductDatasheets

CertificateofAnalysis/ProductDatasheet
SafetyDatasheet