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Tocris/Salirasib/4989/50/50 mg
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4000-520-616
Description:Rasinhibitor;alsoinducesautophagy
ChemicalName:2-[[(2E,6E)-3,7,11-Trimethyl-2,6,10-dodecatrien-1-yl]thio]benzoicacid
Purity:≥98%(HPLC)
BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences
BiologicalActivity
InhibitorofactiveRasproteins.DisplacesactiveRasfromtheplasmamembrane;impairsdownstreamsignalingandinhibitsproliferationofendometrialcarcinomacells.AlsofacilitatesRasdegradation.Showntoinduceautophagyinseveralhumancancercelllines.
TechnicalData
M.Wt | 358.54 |
Formula | C22H30O2S |
Storage | Storeat-20°C |
Purity | ≥98%(HPLC) |
CASNumber | 162520-00-5 |
PubChemID | 5469318 |
InChIKey | WUILNKCFCLNXOK-CFBAGHHKSA-N |
Smiles | CC(CC/C=C(C)/CC/C=C(C)/C)=C/CSC1=CC=CC=C1C(O)=O |
Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.
AllTocrisproductsareintendedforlaboratoryresearchuseonly.
SolubilityData
Solvent | MaxConc.mg/mL | MaxConc.mM | |
---|---|---|---|
Solubility | |||
1eq.NaOH | 17.93 | 50 | |
DMSO | 35.85 | 100 |
PreparingStockSolutions
Thefollowingdataisbasedontheproductmolecularweight358.54.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.
Concentration/SolventVolume/Mass | 1mg | 5mg | 10mg |
---|---|---|---|
1mM | 2.79mL | 13.95mL | 27.89mL |
5mM | 0.56mL | 2.79mL | 5.58mL |
10mM | 0.28mL | 1.39mL | 2.79mL |
50mM | 0.06mL | 0.28mL | 0.56mL |
MolarityCalculator
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ReconstitutionCalculator
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DilutionCalculator
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ProductDatasheets
CertificateofAnalysis/ProductDatasheet
SafetyDatasheet
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